Left ventricular thrombus with a normal heart

Kawamoto, Jun; Ishibashi, Koshiro; Shibukawa, Takanori; Izutani, Hironori

doi:10.1007/s11748-007-0134-6

Cited by 15 publications

(19 citation statements)

References 4 publications

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“…This was followed by semi-rigid endoscopes in four [7, 9, 21, 29], flexible endoscopes in three [2, 3, 30] and mixture of rigid and flexible endoscopes in one study [11]. In 13 studies, the type of endoscope used was not specified [4, 6, 10, 15, 20, 24–28, 31, 34, 35].…”

Section: Resultsmentioning

confidence: 99%

“…In 13 studies, the type of endoscope used was not specified [4, 6, 10, 15, 20, 24–28, 31, 34, 35]. Other adjunct endoscopic instruments such as forceps, graspers, scissors, suckers or retractors were used in 13 studies [2, 3, 12, 13, 15, 19, 21, 25, 30, 32, 34, 35, 37]. In the remaining it was not clear whether open surgical or endoscopic instruments were used.…”

Section: Resultsmentioning

confidence: 99%

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A systematic review of left ventricular cardio-endoscopic surgery

Soylu

Kidher

Ashrafian

et al. 2017

J Cardiothorac Surg

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Better visualisation, accurate resection and avoidance of ventriculotomy associated with use of endoscopic devices during intracardiac surgery has led to increasing interest in their use. The possibility of combining a cardio-endoscopic technique with either minimally invasive or totally endoscopic cardiac surgery provides an incentive for its further development. Several devices have been used, however their uptake has been limited due to uncertainty around their impact on patient outcomes. A systematic review of the literature identified 34 studies, incorporating 54 subjects undergoing treatment of left ventricular tumours, thrombus or hypertrophic myocardium using a cardio-endoscopic technique. There were no mortalities (0%; 0/47). In 12 studies, the follow-up period was longer than 30 days. There were no post-operative complications apart from one case of atrial fibrillation (2.2%; 1/46). Complete resection of left ventricular lesion was achieved in all cases (100%; 50/50). These successful results demonstrate that the cardio-endoscopic technique is a useful adjunct in resection of left ventricular tumours, thrombus and hypertrophic myocardium. This approach facilitates accurate resection of pathological tissue from left ventricle whilst avoiding exposure related valvular damage and adverse effects associated with ventriculotomy. Future research should focus on designing adequately powered comparative randomised trials focusing on major cardiac and cerebrovascular morbidity outcomes in both the short and long-term. In this way, we may have a more comprehensive picture of both the safety and efficacy of this technique and determine whether such devices could be safely adopted for routine use in minimal access or robotic intra-cardiac surgery.Electronic supplementary materialThe online version of this article (doi:10.1186/s13019-017-0599-z) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

A systematic review of left ventricular cardio-endoscopic surgery

Soylu

Kidher

Ashrafian

et al. 2017

J Cardiothorac Surg

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“…Protein C and S deficiency, antiphospolipid syndrome, myeloproliferative disorders, idiopathic hypereosinophilic syndrome, pheochromocytoma, and Takatsubo cardiomyopathy were reported to be related with thrombus formation in patients with a normal LV ejection fraction (8)(9)(10).…”

Section: Discussionmentioning

confidence: 99%

A Case of Thrombus Formation in a Patient with Preserved Left Ventricle Ejection Fraction and Development of Peripheral Embolization

Erkal¹,

Bayar²,

Arslan³

2017

Cyprus J Med Sci

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Echocardiography is a substantial imaging modality for evaluating intracardiac masses. Thrombi and primary or metastatic cardiac tumors should be considered in the differential diagnosis of left ventricle (LV) masses. Thrombus formation in the LV generally occurs because of diseases that cause LV systolic dysfunction. Some cases have been reported to be related to thrombus formation in patients with a normal LV ejection fraction. Physicians should consider that a thrombus might develop in patients with a normal ejection fraction. Keywords: Thrombus, embolization, echocardiography INTRODUCTIONThrombus formation in the left ventricle (LV) generally occurs because of diseases that cause LV systolic dysfunction such as dilated cardiomyopathy, myocardial infarction, and aneurysm. Here we present the case of a patient with an LV thrombus and peripheral embolization and who had a normal LV systolic function.

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“…In the absence of detectable cardiac disease, left ventricular thrombosis is rare and described only anecdotally. Many of these patients have prothrombotic disorders such as protein C deficiency [12], protein S deficiency [13], essential thrombocythemia [14] and antiphospholipid antibody syndrome [15]; however, there are no reports of patients with left ventricular thrombus associated with IDA. Because our patient had no other detectable prothrombotic disorders, we concluded that IDA was the sole cause of left ventricular thrombosis.…”

Section: Discussionmentioning

confidence: 99%

Simultaneous Thrombosis in a Normal Left Ventricle and Normal Carotid Artery in a Patient With a Stroke Secondary to Iron Deficiency Anemia

Nakamizo

2014

J Med Cases

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Iron deficiency anemia (IDA) is implicated as a cause of stroke, particularly in young patients without cardiovascular disease. In such patients, thrombi sometimes form in carotid arteries or the aorta. We report here a patient with a stroke secondary to IDA with thrombi in the normal left ventricle and normal carotid artery. The patient was a 45-year-old woman with severe IDA who developed cerebral infarction in the right middle cerebral artery. She had no other thrombophilia or cardiovascular diseases. Echocardiography showed a left ventricular thrombus without cardiac disease, and the carotid ultrasound showed a mobile thrombus attached to the right internal carotid artery without atherosclerosis. Antithrombotic therapy with iron supplementation removed both thrombi within 2 weeks. This is the first case of IDA with a ventricular thrombus in a normal heart. This case identifies a new site for thrombosis in IDA and shows that patients with IDA may present with simultaneous thrombosis at separate sites. IDA must therefore be recognized as a cause of stroke or systemic embolism, particularly in patients without detectable cardiovascular disease. In such patients, it is important to conduct careful investigations to detect thrombosis.

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Left ventricular thrombus with a normal heart

Cited by 15 publications

References 4 publications

A systematic review of left ventricular cardio-endoscopic surgery

A systematic review of left ventricular cardio-endoscopic surgery

A Case of Thrombus Formation in a Patient with Preserved Left Ventricle Ejection Fraction and Development of Peripheral Embolization

Simultaneous Thrombosis in a Normal Left Ventricle and Normal Carotid Artery in a Patient With a Stroke Secondary to Iron Deficiency Anemia

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