Leiomiosarcoma de pene: presentación de un caso y revisión de la literatura

Abstract

The first case of penile leiomyosarcoma was described by Levi in 1930. In 1957 Ashley and Edwards reported the first case in the British literature and in 1963 Pack reported the first in the American literature. MacKenzie et al. were the first to recognize two types of leiomyosarcoma: superficial and deep. The first develop from smooth muscle cells from the superficial dermal layers of the glans penis or distal third of the penis, they are generally asymptomatic and less malignant, rarely invading deeper structures and without involvement of the urethra on physical exam. The best prognostic predictors are type of tumor at presentation (superficial vs. deep) and treatment choice, being total penectomy more effective for failures of local resections than for primary treatment of deep tumors.

Leiomiosarcoma de prepucio: reporte de un caso

“…El primer caso de LMS de pene fue descripto por Levi en 1930 y hoy, los sarcomas de pene, representan el 5% de las neoplasias en éste órgano 11 .…”

“…Dada su tendencia a recurrir y, sobre todo los más profundos, a dar metástasis, se recomienda escisión quirúrgica de la lesión con amplios márgenes de tejido sano para evitar la recidiva local 9 , 11 . Nuestro caso requirió inicialmente una resección seguida de una ampliación y el paciente está libre de enfermedad luego de 7 meses de seguimiento.…”

Leiomyosarcoma of the Penis, an Exceptional Entity

“…The differential diagnosis includes spindle cell neoplasms such as sarcoma sarcomatoid, Kaposi sarcoma, desmoplastic and spindle cell melanoma, malignant fibrous histiocytoma and leiomyoma, which on the surface must be distinguished from dermatofibrosarcoma protuberans. 7 …”