Leonurus sibiricus L. (honeyweed): A review of its phytochemistry and pharmacology

Sayed, Md. Abu; Alam, Md. Ashraful; Shariful, Islam; Ali, Md. Taif; Ullah, Md. Emdad; Shibly, Abu Zaffar; Ali, M. A.; Hasan-Olive, Md. Mahdi

doi:10.1016/j.apjtb.2016.10.003

Cited by 26 publications

(23 citation statements)

References 23 publications

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“…This medicinal herb is a widely distributed in Asia and South America [15,16]. Phytochemical analysis has revealed the presence of a range of alkaloids, flavonoids, iridoids, diterpenes or phenolic acids I ntis secondary products [17]. It has been reported that extracts obtained from L. sibiricus may demonstrate a range of anti-oxidative, anti-inflammatory and anti-microbial activities [18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

Leonurus sibiricus root extracts decrease airway remodeling markers expression in fibroblasts

Wieczfińska

Sitarek

Kowalczyk

et al. 2020

Clinical and Experimental Immunology

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Airway remodeling is a complex process, and controlling it appears to be a key for halting the progression of asthma and other obstructive lung diseases. The aim of this study was to evaluate the anti‐remodeling properties of extracts from transformed and transgenic L. sibiricus roots with overexpression of AtPAP1 transcriptional factor. Our study shows for the first time that transformed AtPAP1 TR extract from L. sibiricus root may affect the remodeling process.

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Section: Introductionmentioning

confidence: 99%

Leonurus sibiricus root extracts decrease airway remodeling markers expression in fibroblasts

Wieczfińska

Sitarek

Kowalczyk

et al. 2020

Clinical and Experimental Immunology

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“…Most scientific primary sources focus on the study of alkaloids (leonurine and stachydrine) and diterpenoids (147 labdanum diterpenoids). The aerial parts of representatives of the Leonurus genus have been studied to a greater extent [ 8 , 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts

Коshovyi

Raal

Kireyev

et al. 2021

Plants

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The prospect of creating a new medicine with psychotropic activity is shown as a result of studying the chemical composition and pharmacological activity of modified dry extracts of motherwort (Leonurus cardiaca L.) tincture. The most promising substances were the dry extracts, modified by adding small amounts of arginine, valine, phenylalanine, glycine, lysine, and alanine. A total of 15 main phenolic substances were found in the extracts, and eight of them were identified. There were also 10 hydroxycinnamic acids in these extracts, three of which were identified (chlorogenic, caffeic, and rosmarinic acids). The dominant hydroxycinnamic acids were chlorogenic and caffeic acids. Among flavonoids, catechin, hyperoside, and rutin were identified. It should be noted that the extracts had a significant content of ellagic acid. On the basis of the results of the phytochemical analysis of the extracts, it can be concluded that the composition of phenolic compounds does not differ significantly, and the main differences are related to amino acids, which obviously have an impact on the overall pharmacological effect. The results obtained indicate the presence of anxiolytic activity in the motherwort extracts studied in complex with amino acids. The extracts with glycine, valine, and arginine were more effective in reducing anxiety in animals.

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“…A herbaceous annual or biennial medicinal herb, honeyweed (Leonurus sibiricus) could be the alternative to the antibiotic. Due to its bioactive compound such as diterpenes, triterpenes, flavonoids, sterols and phenolic acids, it is effective for the treatment of common diseases like diabetes, cancer, kidney and heart diseases 11 . Analgesic, anti-inflammatory, antioxidant, antimicrobial, anti-hemorrhagic activity have drawn the most attention and it is used in many countries as an herbal medicine 12,13 .…”

Section: Introductionmentioning

confidence: 99%

“…Analgesic, anti-inflammatory, antioxidant, antimicrobial, anti-hemorrhagic activity have drawn the most attention and it is used in many countries as an herbal medicine 12,13 . L. sibiricus has potential pharmacological value both for animal and plant 11 .…”

Section: Introductionmentioning

confidence: 99%

Honeyweed (Leonurus sibiricus) and Buckwheat (Fagopyrum esculentum) supplemented diet improve growth performance, lipid profile and hematological values of broiler chicks

2020

jcbsc

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The study was conducted to investigate the combined effects of honeyweed (HW) and buckwheat (BW) supplemented diets on the growth, feed intake, serum lipid profile and blood parameters in broiler chicks. One hundred fifty (150) day-old chicks (Cobb-500) were divided into five groups viz. T1 (Commercial control, CC), T2 (FF+10% BW), T3 (FF+10% BW+5% (w/v) HW powder), T4 (FF+10% BW+10% (w/v) HW powder), T5 (FF+10% BW+15% (w/v) HW powder) in complete randomized design with five (5) replications, each of which contain six (6) birds. The CC feed and the FF with HW and BW supplemented diet fed on broiler for 30 days. At the end of the study, the body weight gain, FCR and mortality rate were calculated. It was found that T3 (FF+10% BW +5% (w/v) HW powder) diet significantly (p<0.05) showed the good FCR, mortality rate Honeyweed…. Md. Tanvir Abedin et al.

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Leonurus sibiricus L. (honeyweed): A review of its phytochemistry and pharmacology

Cited by 26 publications

References 23 publications

Leonurus sibiricus root extracts decrease airway remodeling markers expression in fibroblasts

Leonurus sibiricus root extracts decrease airway remodeling markers expression in fibroblasts

Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts

Honeyweed (Leonurus sibiricus) and Buckwheat (Fagopyrum esculentum) supplemented diet improve growth performance, lipid profile and hematological values of broiler chicks

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