Les carcinomes de la thyroïde: profils épidémiologique, clinique et thérapeutique, à propos de 102 cas

Touati, Mohamed; Aljalil, Abdelfattah; Darouassi, Youssef; Chihani, Mehdi; Lahkim, Mohamed; Fihri, Jawad Fassi; Bouaity, Brahim; Ammar, Haddou

doi:10.11604/pamj.2015.21.59.5688

Cited by 8 publications

(7 citation statements)

References 10 publications

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“…PTC was the most common histological subtype. These results are consistent with those of African and world series, 8–12 and with those of the Tunisian registry of cancers that reported a mean age of 47.4 years in men and 46.0 years in women. A Tunisian study of 318 differentiated thyroid carcinomas, 14 reported a female predominance of 87.73% and a sex ratio M/F of 0.13.…”

Section: Discussionsupporting

confidence: 92%

“…PTMC accounted for 37.5% of total cases and 42.1% of PTCs. Similar results were reported in the literature 10,12,17,18 . The increase in the incidence and the rate of PTMC is related to the improvement of diagnostic means (cervical ultrasound and fine needle aspiration) allowing the detection of these tumors at a subclinical stage.…”

Section: Discussionsupporting

confidence: 87%

“…Similar results were reported in the literature. 10,12,17,18 The increase in the incidence and the rate of PTMC is related to the improvement of diagnostic means (cervical ultrasound and fine needle aspiration)…”

Section: Discussionmentioning

confidence: 99%

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Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

Ben Thayer,

Khanchel,

Helal

et al. 2023

World j. otorhinolaryngol.-head neck surg.

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BackgroundThyroid carcinoma (TC) accounts for almost 0.5%–1% of total malignancies. Its incidence is increasing rapidly worldwide. Several studies have drawn up the epidemiological profile of TC and its clinical and pathological features. However, to date, no similar studies have been conducted in Tunisia.AimsTo establish an epidemiological profile of TC in a Tunisian health care institute and to analyze its clinical and histopathological characteristics in our institute.Materials and MethodsWe present a retrospective study reviewing the cases of TC diagnosed in our institution in a 4‐year period.ResultsWe collected a sample of 192 cases of TC. It consisted of 31 males and 161 females (83.8%) with a sex‐ratio M/F of 0.19. The mean age was 46.4 years. Papillary thyroid carcinoma was the most frequent histological subtype. The multifocality rate was 33.8%. The mean size of TC was 2.2 ± 1.9 cm. 60.9% of TC were staged pT1 and 20.3% had nodal involvement. Papillary thyroid microcarcinomas were noted in 37.5% of cases.ConclusionOur results were consistent with those of the literature. A high proportion of pT1 and pN0 tumors were noted in our series, suggesting that TC's diagnosis and management was performed at an early stage of the disease in our institution. In addition, our study enabled us to notice the impact of the Coronavirus disease 19 crisis on the management of TC in our institution. Further studies are needed to establish the epidemiological profile of TC in Tunisia and to assess its clinical and pathological features.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 87%

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Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

Ben Thayer,

Khanchel,

Helal

et al. 2023

World j. otorhinolaryngol.-head neck surg.

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“…Five to ten percent of thyroid nodules are malignant[ 3 - 6 ]. Thyroid cancer only represents 1% of all cancers worldwide[ 7 , 8 ] but has occupied the fifth position among all cancers in France and Canada in women in terms of incidence and twentieth in terms of mortality in 2005[ 9 - 11 ]. The improvement of diagnostic techniques by means of thyroid ultrasound, fine needle aspiration, Computed Tomography scan and detailed histopathological analyses partly explains the increase in incidence of thyroid cancer[ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Proportion of thyroid cancer and other cancers in the democratic republic of Congo

Bukasa-Kakamba,

Bangolo,

Bayauli

et al. 2023

World J Exp Med

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BACKGROUND Cancer diagnosis is increasing around the world and in the Democratic Republic of the Congo (DRC). The proportion of thyroid cancer has increased over the past three decades. There are very few studies on cancer epidemiology, and in particular on thyroid cancer in the DRC. AIM To establish the most recent proportion of thyroid cancer in the DRC compared to other cancers. METHODS This is a retrospective and descriptive study of 6106 consecutive cancer cases listed in the pathological registers of 4 Laboratories in the city of Kinshasa. This study included all cancer cases recorded in the registers between 2005 and 2019. RESULTS From a sample of 6106 patients, including all cancer types, 68.3% cases were female and 31.7% were male. Breast and cervical cancer were the most common types of cancer in women and, prostate and skin cancer were the most common types in men. Thyroid cancer was sixth in proportion in women and eleventh in men compared to all cancers. Papillary carcinoma was the most common of thyroid cancers. Rare cancers such as anaplastic and medullary thyroid carcinomas had a proportion of 7% and 2%, respectively. CONCLUSION Newer diagnostic tools led to a surge in cancer diagnoses in the DRC. Thyroid cancer has more than doubled its proportion over the last several decades in the country.

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“…Papillary microcarcinoma of the thyroid have a rather strict histological definition demarcated by the World Health Organization in 1988 as cancers having a diameter equal or inferior to 10 mm in the anatomopathological examination [1]. They established, then, that microcarcinomas constitute about 30% of all papillary carcinomas and about 40% in 2003, making it the most common variant of papillary carcinoma in the United States.…”

Section: Introductionmentioning

confidence: 99%

Papillary Microcarcinoma: AN Epidemiological, Clinical, therapeutic and Prognostic Study of 35 Cases

Hakimi

Hadid

Rochdi

et al. 2020

EJMED

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Papillary microcarcinoma of the thyroid is defined as cancers having a diameter equal or inferior to 10 mm in the anatomopathological examination; The problematic of this pathology lies in its latent character, it is, thus, much more frequent than we thought or predicted. That is why, beyond specifying the epidemiological and clinical characteristics of papillary thyroid microcarcinoma, our ultimate goal was to determine the "gold standard" for the management of this entity. We carried out a descriptive retrospective study spread over 4 years including all cases of Papillary Microcarcinoma of the thyroid diagnosed within the department of ENT and Head and Neck Surgery of the medical center Mohammed VI in Marrakech; We collected 35 cases, and using their medical records we summarized their epidemiological, clinical and paraclinical data. None of our patients had a normal clinical examination, the palpation of our patients showed an isolated nodule in 20% of patients, the rest of our patients had clinically bilateral noticeable nodes. 80% of which were not clinically suspicious, and only three of our patients had palpable lymph nodes which was confirmed by the ultrasound, where the major suspicious character was their hypoechoic character ( 17 % were EU-TIRADS 5 ) With regard to surgical treatment, 28 of our patients (80%) underwent total thyroidectomy as a first step,4 patients underwent secondary totalization during the same operation after the extemporaneous examination came back positive for papillary microcarcinoma , 2 cases of remote loboisthmectomy after final histological examination showing papillary microcarcinoma , and one final case of totalization after extemporaneous examination of a superior right jugular lymph node with central necrosis. Neck dissection was performed in three cases. Postoperative outcomes were simple in all patients. Isotopic totalization by iodine 131 therapy was performed in four of our patients. Their indications were respectively: infiltrating tumor, extension to neighboring parenchyma, multifocality, lymph node metastasis. The survival rate of our series was 100%. The therapeutic protocol of papillary microcarcinoma is punctuated, to this day, with controversy, and faces a conservative attitude versus a radical one, it is the surgeon's duty to distinguish between the two attitudes.

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Les carcinomes de la thyroïde: profils épidémiologique, clinique et thérapeutique, à propos de 102 cas

Cited by 8 publications

References 10 publications

Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

Proportion of thyroid cancer and other cancers in the democratic republic of Congo

Papillary Microcarcinoma: AN Epidemiological, Clinical, therapeutic and Prognostic Study of 35 Cases

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