Lessons from a patient partnership intervention to prevent adverse drug events

Abstract

Partnering with in-patients to prevent adverse drug events is a promising strategy but requires further study to document its efficacy.

Adverse drug events in hospitals: a systematic review

“…Twenty-eight articles remained 6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33 for evaluation, plus one more article retrieved by manual search 34 . Table 1 describes the studies, conducted in 13 countries from North America, Europe, South America, and Asia.…”

“…Table 1 describes the studies, conducted in 13 countries from North America, Europe, South America, and Asia. Ten studies 8,9,15,16,18,19,22,23,24,28 (34.5%) were conducted in the United States and two (6.9%) in Brazil 20,29 .…”

“…Most of the studies were performed in one hospital (19/29) 7,8,12,13,15,16,17,18,19,20,21,25,26,27,28,31,32,33,34 . Six were multi-center 6,9,22,23,24,29 and Figure 1 Flowchart of systematic article search and selection on in-hospital adverse drug events.…”

“…Interestingly, 62.1% of the studies (18/29) 6,7,8,9,12,13,15,16,19,20,21,22,25,26,27,31,33,34 involved university, academic, or teaching hospitals, i.e., presumably large-scale, high-complexity hospital units.…”

“…Forty-eight percent of the studies (14/29) 6,8,9,14,18,19,22,23,24,25,28,29,30,31 used a retrospective approach, i.e., the presence of ADEs was analyzed after the patient was discharged; 48.3% of the studies (14/29) 7,11,12,13,15,16,17,20,21,26,27,32,33,34 used a prospective approach, whereby the ADEs were identified during the hospital stay; and one study 10 was cross-sectional, where ADEs were identified using a survey. Among the studies with a prospective approach, two used retrospective strategies to complement the evaluation, based on an analysis of hospital discharge forms 16,21 .…”