Lessons learnt from an unsuccessful clinical trial of homœopathy

Jansen, Gerard; Veer, A.L.J.v.d.; Hagenaars, Julia C.J.P.; Kuy, A.v.d.

doi:10.1016/s0007-0785(05)80558-7

Br Homeopath J

1992

DOI: 10.1016/s0007-0785(05)80558-7

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Lessons learnt from an unsuccessful clinical trial of homœopathy

Gerard Jansen¹,

A.L.J.v.d. Veer²,

Julia C.J.P. Hagenaars³

et al.

Abstract: In a randomized, double-blind study, the effects of individualized homœopathy in patients suffering from proctocolitis were investigated. The study was controlled against conventional therapy and placebo.Individually indicated homoœopathic medicines were prescribed in the 30c, 200c or 1,000c potencies.The researchers did not succeed in attracting sufficient numbers of participants to arrive at statistically significant conclusions. The total number of patients in the three combined groups was only 20, which wa… Show more

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Priorities and methods for developing the evidence profile of homeopathy Recommendations of the ECH General Assembly and XVIII Symposium of GIRI

Wassenhoven¹

2005

Homeopathy

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To achieve scientific acceptance, homeopathy must investigate several questions: 1. The activity of very highly diluted preparations. The consensus of the meeting was that there is clear evidence of this. 2. The content of very highly diluted homeopathic preparations. More research is needed but evidence exists that a specific signal is present in homeopathic preparations. 3. A theoretical framework in which the effects of homeopathic diluted preparations can be explained. The 'Body Information Theory' is such a theory. 4. The clinical effectiveness of homeopathy. Because they avoid the placebo effect, animal studies are a priority. For human trials using Quality of Life questionnaires, studies on the activity, content and theoretical basis of homeopathic preparations were reviewed approximately 70% of cases; more in children showed improvement. Homeopathy reduced costs and allowed a better improvement in work-days lost compared with conventional practice. Randomised controlled trials (RCTs) implicitly test the placebo hypothesis; RCTs have been performed and meta-analyses conclude that there is clear evidence of efficacy which cannot be attributed to placebo effect. Priorities depend on the audience. More research is needed especially regarding the content of homeopathic preparations and the transmission of information. Theoretical issues are also important to avoid incorrect design of research protocols. More effort should be dedicated to veterinary research. Clinical effects analysis in humans remains important. Many other questions should be prioritised, such as the potential of homeopathy to avoid invasive procedures in children and the long-term effects of homeopathy in preventing chronic complications.

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Priorities and methods for developing the evidence profile of homeopathy Recommendations of the ECH General Assembly and XVIII Symposium of GIRI

Wassenhoven¹

2005

Homeopathy

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Model validity of randomised placebo-controlled trials of individualised homeopathic treatment

Mathie

Wassenhoven²,

Jacobs

et al. 2015

Homeopathy

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Complaints and diagnoses in homoeopathic practice

Jansen¹,

Koster²

1995

Br Homeopath J

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As part of a 4-phase research project, 58 homoeopathic physicians, all members of VHAN (Dutch Association of Homoeopathic Physicians) registered for 1 week the complaints and diagnoses according to ICPC-code of the first 30 patients given exclusively homoeopathic treatment during that week. A total of 1712 patients, 36% male and 64% female, was registered. Children under 10 and adults from 30–40 years particularly sought homoeopathic treatment.

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Lessons learnt from an unsuccessful clinical trial of homœopathy

Cited by 6 publications

References 3 publications

Priorities and methods for developing the evidence profile of homeopathy Recommendations of the ECH General Assembly and XVIII Symposium of GIRI

Priorities and methods for developing the evidence profile of homeopathy Recommendations of the ECH General Assembly and XVIII Symposium of GIRI

Model validity of randomised placebo-controlled trials of individualised homeopathic treatment

Complaints and diagnoses in homoeopathic practice

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