Lethal and sublethal body residues for PCB intoxication in the oligochaete, Lumbriculus variegatus

Fisher, Susan W.; Chordas, Stephen W.; Landrum, Peter F.

doi:10.1016/s0166-445x(98)00103-9

Cited by 47 publications

(58 citation statements)

References 36 publications

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“…Reproduction was only statistically greater than the control in the 59 and 95 g g Ϫ1 treatments when expressed as increases fluoranthene in sediment, the worms had body residues (0.19 Ϯ 0.02 mmol kg Ϫ1 ) that were below concentrations of DDE and PCB congeners (0.34-0.56 mmol kg Ϫ1 ) delivered through contaminated food that had previously been demonstrated to produce reductions in reproduction (Fisher et al 1999). However, there was no expectation of an increase relative to the controls.…”

Section: Reproduction and Growthmentioning

confidence: 77%

“…Mortality was not a very sensitive endpoint for this species; significant mortality was observed in the range of 0.5-1.4 mmol kg Ϫ1 after 35 days of exposure. Reductions in biomass and reproduction were found at lower concentrations, 0.3-0.6 mmol kg Ϫ1 (Fisher et al 1999). Based on the apparent sensitivity of sediment reworking compared to growth from the endrin data mentioned here, it is likely that changes in the sediment reworking rate will occur at body residue concentrations lower than those that affect growth.…”

mentioning

confidence: 73%

“…At the higher exposures, the worms after 10 days of exposure had concentrations where 50% mortality by narcosis (2-8 mmol kg Ϫ1 ) has been observed in some organisms (McCarty and Mackay 1993) but dropped below that level by 28 days. However, the 28-days concentrations were in the range where significant reductions in survival have been observed after 35 days in L. variegatus exposed to DDE or PCB congeners (0.88 -1.35 mmol kg Ϫ1 ; Fisher et al 1999). The treatment concentrations, except for the 59 g g Ϫ1 , resulted in tissue residues that were in the range that produced reductions in biomass or reproduction when L. variegatus were exposed to DDE or PCB congeners (0.34 mmol kg Ϫ1 or greater; Fisher et al 1999).…”

mentioning

confidence: 92%

“…However, the 28-days concentrations were in the range where significant reductions in survival have been observed after 35 days in L. variegatus exposed to DDE or PCB congeners (0.88 -1.35 mmol kg Ϫ1 ; Fisher et al 1999). The treatment concentrations, except for the 59 g g Ϫ1 , resulted in tissue residues that were in the range that produced reductions in biomass or reproduction when L. variegatus were exposed to DDE or PCB congeners (0.34 mmol kg Ϫ1 or greater; Fisher et al 1999). However, no reductions in reproduction were observed for the 95 and 108 g g Ϫ1 treatments, and the biomass was essentially constant among the treatments assuming the 90% survival for higher doses.…”

mentioning

confidence: 92%

“…In L. var-iegatus, the toxicity of selected polychlorinated biphenyl congeners and DDE were examined using growth, mortality, and reproduction as endpoints (Fisher et al 1999). Mortality was not a very sensitive endpoint for this species; significant mortality was observed in the range of 0.5-1.4 mmol kg Ϫ1 after 35 days of exposure.…”

mentioning

confidence: 99%

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Biological Responses of Lumbriculus variegatus Exposed to Fluoranthene-Spiked Sediment

Landrum

Gedeon

Burton³

et al. 2002

Arch. Environ. Contam. Toxicol.

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Abstract. Lumbriculus variegatus was used as a bioassay organism to examine the impact of the sediment-associated polycyclic aromatic hydrocarbon (PAH) fluoranthene on behavior, reproduction, and toxicokinetics. The number of worms increased between the beginning and end of the experiment at 59 g g Ϫ1 fluoranthene, but at the next higher treatment (108 g g Ϫ1 ) the number of worms found was lower and not different from the control. Worms exposed to 95 g g Ϫ1 also exhibited increased reproduction when fed a yeast-cerophyltrout chow mixture. On a total biomass basis, only the 95 g g Ϫ1 exposure with food exhibited a statistically significant increase over the nonfed control. Evaluation of reproduction at the two highest treatments was compromised by a brief aeration failure 2 days before the end of the experiment. The behavioral responses were followed as changes in biological burial rate (sediment reworking rate) of a 137 Cs-labeled marker layer. The biological burial rate increased toward a plateau as the concentration increased from the control (3.9 g g Ϫ1 dry weight total PAH) to 355 g g Ϫ1 dry weight fluoranthene in sediment. The aeration failure had minimal impact on the determination of reworking rate because all the data for the rate determination were collected prior to the aeration failure. Uptake and elimination rates declined with increasing treatment concentration across the range of fluoranthene concentrations, 59 -355 g g Ϫ1 dry weight sediment. The disconnect between the increasing biological burial rates and the decreasing toxicokinetics rates with increasing exposure concentration demonstrates that the toxicokinetic processes are dominated by uptake and elimination to interstitial water. The bioaccumulation factor (concentration in the organisms on a wet weight basis divided by the concentration in sediment on a dry weight basis) ranged from 0.92 to 1.88 on day 10 and declined to a range of 0.52 to 0.99 on day 28 with the lowest value at the highest dose.

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Section: Reproduction and Growthmentioning

confidence: 77%

mentioning

confidence: 73%

mentioning

confidence: 92%

mentioning

confidence: 92%

mentioning

confidence: 99%

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Biological Responses of Lumbriculus variegatus Exposed to Fluoranthene-Spiked Sediment

Landrum

Gedeon

Burton³

et al. 2002

Arch. Environ. Contam. Toxicol.

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A critical body residue approach for predicting persistent bioaccumulative toxicant effects on reproduction and population dynamics of meiobenthic copepods

Chandler

Ferguson

Klauber

et al. 2012

Enviro Toxic and Chemistry

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Critical body residues (CBRs) are the measured tissue toxicant concentrations yielding a median dose-response on a dry-weight or lipid-normalized basis. They facilitate management decisions for species protection using tissue analysis. Population CBR is the mean dose yielding 50% population suppression and was predicted here in Amphiascus tenuiremis for fipronil sulfide (FS) using lifetables and the Leslie matrix. Microplate bioassays (ASTM E-2317-14) produced biomass sufficient for dry mass and lipid-normalized CBR estimates of reproduction (fertility) and population growth suppression. Significant FS toxic effects were delayed naupliar development (at ≥0.10 µg L(-1)), delayed copepodite development (at 0.85 µg L(-1)), decreased reproductive success (at ≥ 0.39 µg L(-1)), and decreased offspring production (at 0.85 µg L(-1)). A reproductive median effective concentration (EC50) of 0.16 µg L(-1) (95% CI: 0.12-0.21 µg L(-1)) corresponded to an adult all-sex CBR and lipid-normalized CBR of 0.38 pg FS · µg(-1) dry weight (95% CI: 0.27-0.52 pg FS · µg(-1)) or 2.8 pg FS · µg(-1) lipid (95% CI: 2.2-3.6 pg FS · µg(-1)), respectively. Copepod log bioconcentration factor (BCF) = 4.11 ± 0.2. Leslie matrix projections regressed against internal dose predicted fewer than five gravid females in a population by the third generation at 0.39 and 0.85 µg FS · L(-1) (i.e., 9.6-10.2 µg FS · µg(-1) lipid), and 50% population suppression at a CBR of 1.6 pg FS · µg(-1) lipid. This more integrative population CBR as a management tool would fall 1.75 times below the CBR for the single most sensitive endpoint-fertility rate.

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Application of a Tenax model to assess bioavailability of PCBs in field sediments

Mackenbach

You

Mills

et al. 2012

Enviro Toxic and Chemistry

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Bioavailability has been estimated in the past using equilibrium partitioning-based biota-sediment accumulation factors. These values are not always reliable using field-collected sediments, however, likely due to varying amounts of different organic carbons, particularly black carbon, in sediments. Therefore, improving approaches to better evaluate contaminant bioavailability in sediment are needed. In the present study, a literature-based model was constructed that relied on both laboratory-exposed and field-collected oligochaete bioaccumulation data. The model system used 24-h Tenax extraction data paired with bioaccumulation tests using oligochaetes to establish the ability and utility of the biomimetic extraction. The model was then tested to confirm its utility and reliability to estimate bioavailability of oligochaetes exposed to polychlorinated biphenyl (PCB) contaminated sediments from the Ottawa River in Ohio, USA. The model correctly identified the bioaccumulation of PCBs for 94.9% of the data and 97% of the dioxin-like congeners. The mono- and di-substituted chlorinated biphenyls were the least well described, but the estimates were conservative, for example, the model overpredicted bioaccumulation. Thus, the Tenax model was robust and reliable across a wide range of sediment characteristics for estimating PCB bioaccumulation in oligochaetes.

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Lethal and sublethal body residues for PCB intoxication in the oligochaete, Lumbriculus variegatus

Cited by 47 publications

References 36 publications

Biological Responses of Lumbriculus variegatus Exposed to Fluoranthene-Spiked Sediment

Biological Responses of Lumbriculus variegatus Exposed to Fluoranthene-Spiked Sediment

A critical body residue approach for predicting persistent bioaccumulative toxicant effects on reproduction and population dynamics of meiobenthic copepods

Application of a Tenax model to assess bioavailability of PCBs in field sediments

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