Letter to Editor

Hall, Jean A.; Obare, Edward; Yerramilli, Maha; Melendez, Lynda D.; Jewell, Dennis E.

doi:10.1111/jvim.13803

Cited by 2 publications

(3 citation statements)

References 6 publications

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“…Creatinine assembly fluctuations significantly according to the muscle mass of the body and dietary factors . Creatinine is filtered by the glomeruli, and also secreted by the renal tubules .…”

Section: Discussionmentioning

confidence: 99%

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Relevance of cystatin‐C, N‐acetylglucosaminidase, and Interleukin‐18 with the diagnosis of acute kidney injury induced by cadmium in rats

Ali

Elshaer

Anwar

et al. 2017

J Biochem & Molecular Tox

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The diagnosis of acute kidney injury (AKI) is frequently established on modifications in serum creatinine (SCr). The discriminative and prognostic aptitudes of serum cystatin-C as well as N-acetylglucosaminidase (NAG) and Interleukin-18 (IL-18) were inspected for the estimation of AKI. In this study twelve rats were alienated into two groups: control group received saline, second group received cadmium chloride at a dose (2.4 mg Cd/kg/day, i.p) for 30 days. Blood urea nitrogen (BUN), SCr, and IL-18 serum level were measured in addition to serum and tissue content of cystatin-C and NAG. AKI model showed significant increase in BUN, creatinine, and IL-18. RT-PCR showed upregulation of cystatin-C gene besides significant increase of its level in serum. Additionally, tissue content of NAG was significantly increased. Our findings may provide that grouping of several biomarkers for diagnosis of AKI is a more valuable diagnostic tool than single-marker measurement.

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Section: Discussionmentioning

confidence: 99%

“…Creatinine assembly fluctuations significantly according to the muscle mass of the body and dietary factors. [14] Creatinine is filtered by the glomeruli, and also secreted by the renal tubules. [15] This tubular secretion subsidizes circa 20% of the total creatinine excretion by the kidney and it can surge as GFR declines.…”

Section: Discussionmentioning

confidence: 99%

Relevance of cystatin‐C, N‐acetylglucosaminidase, and Interleukin‐18 with the diagnosis of acute kidney injury induced by cadmium in rats

Ali

Elshaer

Anwar

et al. 2017

J Biochem & Molecular Tox

View full text Add to dashboard Cite

show abstract

“…12 The serum creatinine (sCr) and serum urea nitrogen (SUN) reference concentration ranges for adult dogs are 0.42−1.03 mg/dL (2.45-fold) and 7.1−25.6 mg/dL (3.61-fold), respectively. 13 The fixed 81-fold span of E-AB sensors sacrifices its precision in reflecting the small changes in the narrow range of these target concentrations. Therefore, obtaining a tunable detection range is crucial for the practical application of E-AB sensors.…”

mentioning

confidence: 99%

Electrochemical Aptamer-Based Sensors with Tunable Detection Range

Pan

et al. 2023

Anal. Chem.

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Letter to Editor

Cited by 2 publications

References 6 publications

Relevance of cystatin‐C, N‐acetylglucosaminidase, and Interleukin‐18 with the diagnosis of acute kidney injury induced by cadmium in rats

Relevance of cystatin‐C, N‐acetylglucosaminidase, and Interleukin‐18 with the diagnosis of acute kidney injury induced by cadmium in rats

Electrochemical Aptamer-Based Sensors with Tunable Detection Range

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