Letter to ESCD members

Basketter, David A.

doi:10.1034/j.1600-0536.2002.470408.x

Cited by 1 publication

(2 citation statements)

References 6 publications

(6 reference statements)

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“…It should also be noted that many of these early cases of contact allergy were observed in patients with pre‐existing skin disease, such as hand eczema, where the barrier integrity of the skin may be compromised and where there is known to be an increased risk of contact allergy 33 . More recent data indicate that MCI/MI contact allergy has decreased significantly, is stable, and affects 1–3% of patch‐tested patients in European centers 34–36 …”

Section: Preservativesmentioning

confidence: 99%

“…33 More recent data indicate that MCI/MI contact allergy has decreased significantly, is stable, and affects 1-3% of patch-tested patients in European centers. [34][35][36] An essential element of the dermal sensitization risk assessment process is the evaluation and understanding of the relationship between dermal sensitization hazard (the inherent potential of an ingredient to cause dermal sensitization) and actual dermal sensitization risk. The latter relates to the induction of contact allergy under exposure conditions typical of all intended and foreseeable uses of the product by consumers.…”

Section: Preservativesmentioning

confidence: 99%

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Safety of cosmetic products

Engasser

Long²,

Maiello³

et al. 2007

J of Cosmetic Dermatology

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Summary Background While technological advances have spurred innovations in product development and testing, often dermatologists and consumers are not aware of the extensive processes that manufacturers use to ensure that products are safe. In all of the major markets around the world, laws require that every cosmetic or personal care product on store shelves be safe for their intended use. The assessment of cosmetic product safety is a multistep process that spans the various stages of the product development/marketing cycle. Extensive testing to ensure safety is an integral and ongoing part of this product development cycle. Aims In this paper we attempt to distill the most relevant information on the science of cosmetic safety assessment in order to enhance our understanding of cosmetics and how to use this knowledge to increase consumer and patient safety. We will review a wide range of topics, including the current best practices of reputable manufacturers for ensuring product safety, the regulatory environment for cosmetics, as well as research in contact dermatitis related to cosmetics. We will also review the most recent data related to two topics that receive a significant amount of attention these days: preservatives and fragrances. Conclusion Today, regulatory bodies around the world have set rigorous standards for product safety, while improved technology has made testing more efficient. Ongoing research continues to generate improvements in the way products are developed and evaluated – from start to finish. By using the latest scientific advances and good manufacturing practices, cosmetic manufacturers are putting products through cutting‐edge paces designed to maximize safety.

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Section: Preservativesmentioning

confidence: 99%