Letter to the Editor

Bell, Edward F.; E, Ziegler; Forbes, George

doi:10.1203/00006450-198404000-00021

Cited by 51 publications

(10 citation statements)

References 3 publications

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“…Bromide space was calculated as dose of bromide/(the concentration of bromide in serum at 4 h postdose Ϫ the concentration of bromide in the baseline serum sample). ECWref was calculated as bromide space ϫ 0.90 ϫ 0.95 ϫ 0.94 (3).…”

Section: Methodsmentioning

confidence: 99%

Evaluation of bioimpedance spectroscopy for measurements of body water distribution in healthy women before, during, and after pregnancy

Löf

Forsum

2004

Journal of Applied Physiology

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Bioimpedance spectroscopy (BIS) is a technique of interest in the study of human pregnancy because it can assess extracellular (ECW), intracellular (ICW), and total body water (TBW) as ECW plus ICW. The technique requires appropriate resistivity coefficients and has not been sufficiently evaluated during the reproductive cycle. Therefore, in a methodological study, we estimated ECW, ICW, and TBW, by means of BIS, and compared the results with the corresponding estimates obtained by using reference methods. Furthermore, results obtained by means of population-specific resistivity coefficients were compared with results obtained by means of general resistivity coefficients. These comparisons were made before pregnancy, in gestational weeks 14 and 32, as well as 2 wk postpartum in 21 healthy women. The reference methods were isotope and bromide dilution. Average ICW, ECW, and TBW, estimated by means of BIS, were in agreement with reference data before pregnancy, in gestational week 14, and postpartum. The corresponding comparison in gestational week 32 showed good agreement for ICW, whereas estimates by means of BIS were significantly (P < 0.001) lower than the corresponding reference values for ECW and TBW. Thus the BIS technique, which was based on a model developed for the nonpregnant body, estimated increases in ICW accurately, whereas increases in ECW and TBW tended to be underestimated. Estimates obtained by using population-specific and general resistivity coefficients were very similar. In conclusion, the results indicated that BIS is potentially useful for studies during pregnancy but that further work is needed before it can be generally applied in such studies.

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Section: Methodsmentioning

confidence: 99%

Evaluation of bioimpedance spectroscopy for measurements of body water distribution in healthy women before, during, and after pregnancy

Löf

Forsum

2004

Journal of Applied Physiology

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“…Blood samples (0.8 ml) were obtained prior to the administration of NaBr and 2 h afterward. Serum bromide was analyzed using a spectrophotometric method [15] and expressed as corrected bromide space [14,16]. Body fluid compartments measurements were carried out on day 1 and day 8 of life.…”

Section: Methodsmentioning

confidence: 99%

The Effects of Early Parenteral Amino Acids on Sick Premature Infants

2010

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“…Extracellular water can be estimated from the Corrected Bromide Space (CBS), which was calculated according to the following formula [29]: CBS = Br dose (mmol)/Br in plasma (mmol/l) × 0.90 × 0.95 × 0.94, where 0.90 = correction factor for the distribution of bromide in the non-extracellular sites (principally red blood cells); 0.95 = correction factor for the Donnan equilibrium [30]; 0.94 = correction factor for the concentration of water in the plasma which is about 94%.…”

Section: The Equilibrium Of Bromide Concentration Is Established In Bmentioning

confidence: 99%

Total body water and extracellular water measurements through in vivo dilution of D₂O and bromide as tracers

Sergi

Bertani

Calliari

et al. 2003

Journal of Spectroscopy

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Large interest is into the determination of body fluids because of changes in body water in a wide variety of physiological and pathological conditions. Here methods based on dilution of tracers, are reported, for the extracellular water (ECW) and total body water (TBW) determinations on the same sample. As for ECW, bromide is used as tracer and its concentration is determined by energy dispersive X-ray spectrometry; while as for TBW, D2O is used as tracer and HOD is determined by FT IR. Both methods represent significant improvements with respect the procedures described in the literature in terms of availability, reproducibility and accuracy.

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Letter to the Editor

Cited by 51 publications

References 3 publications

Evaluation of bioimpedance spectroscopy for measurements of body water distribution in healthy women before, during, and after pregnancy

Evaluation of bioimpedance spectroscopy for measurements of body water distribution in healthy women before, during, and after pregnancy

The Effects of Early Parenteral Amino Acids on Sick Premature Infants

Total body water and extracellular water measurements through in vivo dilution of D₂O and bromide as tracers

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Letter to the Editor

Cited by 51 publications

References 3 publications

Evaluation of bioimpedance spectroscopy for measurements of body water distribution in healthy women before, during, and after pregnancy

Evaluation of bioimpedance spectroscopy for measurements of body water distribution in healthy women before, during, and after pregnancy

The Effects of Early Parenteral Amino Acids on Sick Premature Infants

Total body water and extracellular water measurements through in vivo dilution of D2O and bromide as tracers

Contact Info

Product

Resources

About

Total body water and extracellular water measurements through in vivo dilution of D₂O and bromide as tracers