Letter to the Editor Re: Diaz M., et al. Nutrients 2018, 10, 1481

Abstract

We have read with interest the article published by Diaz et al [...]

Reply: “Letter to the editor Re: Diaz M., et al. Nutrients 2018, 10, 1481”

“…The objective of this letter of reply is to provide answers to the doubts and critical issues that Martín Martinez and López Liñan [1] raised in their letter to the editor with respect to the work published last year in Nutrients in the field of microbiota, diet and non-IgE cow's milk protein allergy (NIM-CMPA).…”

“…Secondly, Martín Martinez and López Liñan [1] mentioned that the authors did not provide enough information about the diet of the infants before inclusion, and because the studied infant ages ranges between 13 and 23 months, we should provide information about the type of diet that infants received from diagnosis until the beginning of the study. Probably we did not make these points clear enough in our manuscript.…”

“…That means that at the time of diagnosis, the NIM-CMPA infants were at least 6 months younger than at sampling. In their letter [1], Martín Martinez and López Liñan argue that “another important difference between controls and infants with NIM-CMPA is that the latter followed a diet free of dairy products for 6 months. Indeed, this can be a factor modifying the microbiota”.…”

“…Regarding the comment on the use of vegetable formulas and the possible impairment of tolerance acquisition, Martín Martinez and López Liñan [1] indicate that “this conclusion cannot be drawn from the results of the study from Diaz et al”. However, although these issues are discussed within the discussion section, our manuscript does not establish such a conclusion.…”