Levels of Serum Trace Elements in Renal Cell Carcinoma Cases

Pirinççi, Necip; Geçit, İlhan; Güneş, Mustafa; Kaba, Mehmet; Tanık, Serhat; Yüksel, Mehmet Bilgehan; Arslan, Harun; Demır, Halit

doi:10.7314/apjcp.2013.14.1.499

Cited by 32 publications

(20 citation statements)

References 30 publications

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“…Zinc has a protective effect against free-radical injury (Wu et al, 2004). In previous studies, it has been reported that serum Zn concentrations were decreased in patients with ovarian, cervical, bladder and renal cancer (Cunzhi et al, 2003;Yaman et al, 2007;Pirincci et al, 2013). It is known that Zn concentration is significantly higher in prostate gland when compared to other tissues in human body (Costello et al, 1998).…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, it can be suggested that decreased serum Mn concentrations with disturbance of antioxidant mechanism can make target organs susceptible to carcinogens. Decreased serum Mn concentrations were reported in patients with bladder and renal cancers Pirincci et al;. It was shown that decreased Mn is potentially associated with decreased activity of superoxide dismutase in advanced stages of cancer (Gleason grade 3 or 4) when compared to group with Gleason 2 grade disease (Banas et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

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Serum Levels of Trace Elements in Patients with Prostate Cancer

Kaba¹,

Pirinççi²,

Yüksel³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: Trace elements are major components of biological structures; however, excessive levels of these elements can be toxic. Materials and Methods: In the present study, serum levels of trace elements were measured in 30 patients with newly diagnosed as prostate cancer and 32 healthy volunteer by using furnace atomic absorption spectrophotometry. Results: It was found that there was an increase in serum levels of Co, Cu, Mg and Pb (p<0.05), whereas a decrease in serum levels of Fe, Mn, and Zn levels in patients with prostate cancer (p<0.05). Conclusions: These changes may be important in the pathogenesis of prostate cancers; however, further prospective studies are needed to identify relationships between prostate cancer and trace elements.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Serum Levels of Trace Elements in Patients with Prostate Cancer

Kaba¹,

Pirinççi²,

Yüksel³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…It was discovered by a literature on kidney cancer patients that Cd level was higher than those of healthy people [9]. A study on colon cancer revealed that Cd level was higher than those of healthy people [10] It was presented by a study in Turkey that Cd level in renal cell carcinoma increased significantly compared to healthy people [16]. A study compared Cd levels of glioma cancer patients and healthy people and presented that CD level in glioma patients was significantly higher [17].…”

Section: Discussionmentioning

confidence: 99%

“…Likewise, a research discovered that Pb level in kidney cancer patients was higher than those of healthy people [9]. It was presented by a study in Turkey that Pb level in renal cell carcinoma increased significantly compared to healthy people [16]. A literature on colon cancer found out that Pb level was higher than those of healthy people [10].…”

Section: Discussionmentioning

confidence: 99%

Examination of preoperative and postoperative levels of rare earth elements (Zn, Cu, Mg, Pb, Mn, Cd, Co and Fe in the blood of ovarian cancer patients

2015

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Objective: In this study, serum material drawn preoperatively and postoperatively from totally 33 patients who applied to Department of Gynaecology of Yüzüncü Yıl University Faculty of Medicine and Van Training and Research Hospital due to suffering from ovarian cancer was used. Material and Methods: The serum levels (Zn, Cu, Mg, Pb, Mn, Cd, Co and Fe) were determined by the method of Atomic Absorption Spectrophotometry at Spectrometer in Yüzüncü Yıl University Central Research Laboratory. The levels of rare-earth, trace and heavy elements were determined from the serum samples which were drawn from healthy and volunteer 30 women who were close to the same age group. Results: This study found out a significant difference (p<0.001) between the preoperative and postoperative levels of lead, manganese and iron in ovarian cancer patients. While a significant difference (p>0.005) wasn't discovered between the preoperative and postoperative levels of zinc, copper, cadmium and cobalt in ovarian cancer patients, a statistically significant difference was found between the preoperative and postoperative levels of magnesium (p=0.07) in those patients. Conclusion: Consequently, Zn is important in the prognosis of the disease because it is a strong antioxidant element. The elements Mg, Mn and Fe can be significant markers for ovarian cancer and especially low level of Mn may increase the risk of ovarian cancer. Also, such elements as Zn, Cu, Mg, Pb, Mn, Cd, Co and Fe may play an important role in pathogenesis of ovarian cancer.

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“…Trace elements which are important components of biological structures may also be toxic at levels above the amounts required for biological function (Pirincci et al, 2013). Currently, some trace elements have begun to gain attention in terms of the treatment and diagnosis of stroke since they are essential for sustaining metabolism of neurons and glia (Zangieva et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Levels of serum trace elements in ischemic stroke patients

Gönüllü¹,

Karadaş²,

Milanlıoğlu³

et al. 2014

jecm

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Article HistoryReceived 14 / 08 / 2013 Accepted 17 / 09 / 2013The mortality and morbidity of ischemic stroke (IS) can be decreased by early diagnosis and proper treatment of these patients in the emergency department. The levels of trace elements in the human body are important in maintaining the balance in the various biological components. In this study, we examined the impact of imbalance in levels of trace elements in patients with acute IS. In this prospective study, serum copper (Cu), lead (Pb), cadmium (Cd), zinc (Zn), cobalt (Co), manganese (Mn), and magnesium (Mg) levels were investigated in 25 healthy participants (control group) and 24 IS patients. The Cd, Pb, Co, and Cu levels were significantly higher in the patients compared to control groups (P<0.05), while the levels of Zn, Mg, Mn were lower. The results of our study show that an increase in the levels of Cd, Pb, Co and Cu may be important in the occurrence of IS.

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Levels of Serum Trace Elements in Renal Cell Carcinoma Cases

Cited by 32 publications

References 30 publications

Serum Levels of Trace Elements in Patients with Prostate Cancer

Serum Levels of Trace Elements in Patients with Prostate Cancer

Examination of preoperative and postoperative levels of rare earth elements (Zn, Cu, Mg, Pb, Mn, Cd, Co and Fe in the blood of ovarian cancer patients

Levels of serum trace elements in ischemic stroke patients

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