Lichen Striatus

Tenascin-C Expression in Papulosquamous Disorders Other than Psoriasis in Pediatric Patients: An Epiphenomenon?

“…Based on histologic findings, the primary target of the inflammatory reaction is the keratinocyte in the basal and suprabasal layers. 17 It was the only papulosquamous disorder in which one of the two biopsy samples was negative for tenascin-C immunohistochemically, and this result may be due to the small number of samples.…”

Pediatric Dermatology Photoquiz: Persistent Lesion of the Thumbnail of a 3‐Year‐Old Boy

“…Lichen striatus typically occurs in children younger than 15 years, with girls thought to be affected more commonly than boys, although the disease can occur in patients of any age . Lichen striatus most commonly manifests as small (<5 mm), variably pigmented, flat‐topped papules that very characteristically follow the lines of Blaschko . As a result, lichen striatus generally follows a narrow, unilateral pattern that may be continuous or interrupted.…”

“…Postinflammatory hyper‐ or hypopigmentation may occur after resolution of cutaneous lichen striatus, and this too usually improves over the course of several years. Affected nails similarly resolve without treatment, although complete resolution may take longer, on the order of many months to a few years (with an average duration of approximately 8 mos) .…”