Life stress and first onset of psychiatric disorders in daughters of depressed mothers

Gershon, Anda; Hayward, Chris; Schraedley-Desmond, Pamela; Rudolph, Karen D.; Booster, Genery D.; Gotlib, Ian H.

doi:10.1016/j.jpsychires.2011.03.016

Cited by 40 publications

(48 citation statements)

References 38 publications

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“…Researches have shown consistently that children of depressed mothers are at elevated risk for developing a range of psychiatric disorders, as depression [70][71][72]. This risk persists beyond the duration of a given maternal depressive episode and can continue into adulthood [70,73].…”

Section: Family and Hereditary Factorsmentioning

confidence: 99%

“…This risk persists beyond the duration of a given maternal depressive episode and can continue into adulthood [70,73]. Daughters may be especially vulnerable; investigators have found that daughters of depressed mothers are more likely to develop Psychopathology than are son [70,74,75].…”

Section: Family and Hereditary Factorsmentioning

confidence: 99%

“…In addition to the role of shared adversity, such research should consider the effects of child gender and age, which have not been examined using genetically sensitive designs. As already mentioned, there is evidence that different factors may be involved in the etiology and intergenerational transmission of depression for boys and girls [70]. Some studies found that the association between maternal depression and offspring is stronger in daughters than sons [70,74,75].…”

Section: Family and Hereditary Factorsmentioning

confidence: 99%

“…As already mentioned, there is evidence that different factors may be involved in the etiology and intergenerational transmission of depression for boys and girls [70]. Some studies found that the association between maternal depression and offspring is stronger in daughters than sons [70,74,75]. However, other studies have not reported gender differences [62,80].…”

Section: Family and Hereditary Factorsmentioning

confidence: 99%

“…al. [70] suggest that schools may be a logical place to implement interventions aimed at reducing behavioral stress among children of depressed parents. The findings also suggest that there may be modifiable risk factors, such as the adolescent's coping skills, which can be targeted through early interventions to help identify and change the ways in which stress is self-generated.…”

Section: Preventionmentioning

confidence: 99%

See 4 more Smart Citations

Childhood Depression As Emerging Public Health Problem: A Systematic Review

Pimentel¹,

Júnior²,

Júnior³

et al. 2015

Int Arch Med

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As an important problem of public health, the childhood depression deserves special attention, in which the serious and long term consequences of the disease weigh to the childhood development. Taking this in consideration, the present study was based in the following research question: which practical contribution the actual scientific literature about childhood depression has to offer to clinicians and researchers? The aim of the present study was to evaluate the actual evidence concerning the different aspects (etiology/risk factors, diagnosis, treatment, prognostic and prevention) of childhood depression, with the purpose to systematize such evidences and to contribute with the knowledge about the problem. In way to reach this aim, it was performed a systematic review of articles about childhood depression, in the period from January first of 2010 to January 16 of 2014, in the databases PubMED, MEDLINE and SciELO. In the research, the following terms were used: "depression" (MeSH), "child" (MeSH) and "childhood depression" (Keyword). Of the 860 found studies, 76 met the eligibility criteria. The found studies covered a wide variety of aspects related to childhood depression, as diagnosis, treatment, prevention and prognostic. The actual scientific literature about the childhood depression converges to, directly or not, highlight the negative impacts of the depression disorders to the life quality of the children. Unfortunately, the found studies show that the childhood depression is a disorder that develops most commonly in a poverty and vulnerability scenery, where the individual and familiar necessities concerning the childhood depression are not always taken in consideration. In this context, this review demonstrates that the depression started in

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Section: Family and Hereditary Factorsmentioning

confidence: 99%

Section: Family and Hereditary Factorsmentioning

confidence: 99%

Section: Family and Hereditary Factorsmentioning

confidence: 99%

Section: Family and Hereditary Factorsmentioning

confidence: 99%

Section: Preventionmentioning

confidence: 99%

See 3 more Smart Citations

Childhood Depression As Emerging Public Health Problem: A Systematic Review

Pimentel¹,

Júnior²,

Júnior³

et al. 2015

Int Arch Med

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Association of Multigenerational Family History of Depression With Lifetime Depressive and Other Psychiatric Disorders in Children

et al. 2021

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IMPORTANCE Three-generation family studies of depression have established added risk of psychopathology for offspring with 2 previous generations affected with depression compared with 1 or none. Because of their rigorous methodology, there are few of these studies, and existing studies are limited by sample sizes. Consequently, the 3-generation family risk paradigm established in family studies can be a critical neuropsychiatric tool if similar transmission patterns are reliably demonstrated with the family history method.OBJECTIVE To examine the association of multigenerational family history of depression with lifetime depressive disorders and other psychopathology in children. DESIGN, SETTING, AND PARTICIPANTS In this analysis of the Adolescent Brain Cognitive Development (ABCD) study data, retrospective, cross-sectional reports on psychiatric functioning among 11 200 children (generation 3 [G3]) and parent reports on parents' (G2) and grandparents' (G1) depression histories were analyzed. The ABCD study sampling weights were used for generalized estimating equation models and descriptive analyses. Data were collected from September 2016 to November 2018, and data were analyzed from July to November 2020.MAIN OUTCOMES AND MEASURES Four risk categories were created, reflecting how many prior generations had history of depression: (1) neither G1 nor G2 (G1−/G2−), (2) only G1 (G1+/G2−), (3) only G2 (G1−/G2+), and (4) both G1 and G2 (G1+/G2+). Child lifetime prevalence and relative risks of psychiatric disorders were based on child and caregiver reports and grouped according to familial risk category derived from G1 and G2 depression history. RESULTS Among 11 200 included children, 5355 (47.8%) were female, and the mean (SD) age was 9.9 (0.6) years. By parent reports, the weighted prevalence of depressive disorder among children was 3.8% (95% CI, 3.2-4.3) for G1−/G2− children, 5.5% (95% CI, 4.3-7.1) for G1+/G2− children, 10.4% (95% CI, 8.6-12.6) for G1−/G2+ children, and 13.3% (95% CI, 11.6-15.2) for G1+/G2+ children (Cochran-Armitage trend = 243.77; P < .001). The weighted suicidal behavior prevalence among children was 5.0% (95% CI, 4.5-5.6) for G1−/G2− children, 7.2% (95% CI, 5.8-8.9) for G1+/G2− children, 12.1% (95% CI, 10.1-14.4) for G1−/G2+ children, and 15.0% (95% CI, 13.2-17.0) for G1+/G2+ children (Cochran-Armitage trend = 188.66; P < .001). By child reports, the weighted prevalence of depressive disorder was 4.8% (95% CI, 4.3-5.5) for G1−/G2− children, 4.3% (95% CI, 3.2-5.7) for G1+/G2− children, 6.3% (95% CI, 4.9-8.1) for G1−/G2+ children, and 7.0% (95% CI, 5.8-8.5) for G1+/G2+ children (Cochran-Armitage trend = 9.01; P = .002), and the weighted prevalence of suicidal behaviors was 7.4% (95% CI, 6.7-8.2) for G1−/G2− children, 7.0% (95% CI, 5.6-8.6) for G1+/G2− children, 9.8% (95% CI, 8.1-12.0) for G1−/G2+ children, and 13.8% (95% CI, 12.1-15.8) for G1+/G2+ children (Cochran-Armitage trend = 46.69; P < .001). Similar patterns were observed for other disorders for both parent and child reports and across...

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The Implications of Maternal Obesity on Offspring Physiology and Behavior in the Nonhuman Primate

Sullivan

Kievit

2016

Parental Obesity: Intergenerational Programming and Consequences

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Life stress and first onset of psychiatric disorders in daughters of depressed mothers

Cited by 40 publications

References 38 publications

Childhood Depression As Emerging Public Health Problem: A Systematic Review

Childhood Depression As Emerging Public Health Problem: A Systematic Review

Association of Multigenerational Family History of Depression With Lifetime Depressive and Other Psychiatric Disorders in Children

The Implications of Maternal Obesity on Offspring Physiology and Behavior in the Nonhuman Primate

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