Lifestyle Changes and Exacerbation Frequency of COPD in Times of the Pandemic

Chronic Obstructive Pulmonary Disease Mortality and Hospitalization during the COVID-19 Pandemic Compared with before the Pandemic: A Systematic Review and Meta-Analysis

“…The studies included eleven with the outcome of mortality [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ] and eleven with the outcome of hospitalization for AECOPD [ 22 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ]. Dang et al reported the outcomes of mortality and hospitalization rates for AECOPD [ 22 ].…”

“…There were eleven multicenter [ 22 , 23 , 25 , 26 , 28 , 29 , 30 , 32 , 35 , 39 , 40 ] and ten single-center studies. Fifteen studies were observational cohort studies [ 21 , 22 , 23 , 24 , 25 , 26 , 28 , 29 , 32 , 34 , 35 , 37 , 38 , 39 ], and six studies were letters or conference abstracts [ 20 , 27 , 30 , 34 , 37 , 40 ] ( Table 1 ).…”

“…For the Newcastle–Ottawa Scale result, all studies had four points in the selection domain and one point in the outcome assessment. Eight studies had two additional points after adjusting for confounding factors [ 22 , 23 , 24 , 25 , 29 , 32 , 35 , 38 ] ( Supplementary Table S2 ).…”

“… Forest plot for admission of AECOPD during the COVID-19 pandemic compared with before the pandemic [ 22 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ]. …”

“…The following supporting information can be downloaded at: , Table S1: Search strategy; Table S2: Quality assessments in individual studies by Newcastle–Ottawa tool; Figure S1: Forest plot of subgroup analysis for the in-hospital mortality of AECOPD during the COVID-19 pandemic compared with before the pandemic; Figure S2: Forest plot of subgroup analysis for the hospitalization of AECOPD during the COVID-19 pandemic compared with before the pandemic; Figure S3: Funnel plot. References [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ] are cited in the supplementary materials.…”