Light flickering through a narrow window opening in capsule panendoscopy

Valdivia, Pablo Cortegoso; Tóth, Ervin; Koulaouzidis, Anastasios

doi:10.1055/a-1782-3378

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…However, after PCE establishment, there has been a shift in this classical scenario, due to hypothetical advantages associated with this innovative diagnostic procedure. On one hand, capsule endoscopy now allows the examination of all GI segments on a single procedure [ 47 ]. Furthermore, an adequately timed pan-enteric evaluation may eventually avoid unnecessary inconclusive examinations, with subsequent organizational and economic benefits, as described by Rondonotti et al [ 48 ].…”

Section: Clinical Applicationsmentioning

confidence: 99%

Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives

Rosa,

Andrade,

Lopes

et al. 2023

GE Port J Gastroenterol

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Background: The role of capsule endoscopy in the evaluation of the small bowel is well established, and current guidelines position it as a first-line test in a variety of clinical scenarios. The advent of double-headed capsules further enabled the endoscopic assessment of colonic mucosa and the opportunity for a one-step noninvasive examination of the entire bowel (pan-enteric capsule endoscopy [PCE]). Summary: We reviewed the technical procedure and preparation of patients for PCE, as well as its current clinical applications and future perspectives. In non-stricturing and non-penetrating Crohn’s disease affecting the small bowel and colon, PCE monitors disease activity by assessing mucosal healing, a major treatment outcome, with a higher diagnostic yield than cross-sectional imaging or conventional colonoscopy. Also in ulcerative colitis, double-headed capsules have been used to monitor disease activity noninvasively. Currently, validated scoring systems have been specifically devised for these double-headed capsules and permit a standardized assessment of the inflammatory burden. In suspected mid-lower digestive bleeding, some exploratory studies have demonstrated the feasibility and high diagnostic yield of PCE, which may work as a filter indicating which patients may benefit of further invasive procedures, namely, for planned hemostatic procedures. The possibility of using PCE is also discussed in the context of polyposis syndromes with simultaneous involvement of the small intestine and colon. Key Messages: PCE is a feasible, effective, and safe diagnostic procedure to evaluate the small bowel and colon. It has been increasingly explored in the setting of inflammatory bowel diseases and, more recently, in suspected mid-lower digestive bleeding. PCE is expected to reduce the demand for invasive procedures and expand the scope of noninvasive intestinal evaluation in the coming future.

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Section: Clinical Applicationsmentioning

confidence: 99%

Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives

Rosa,

Andrade,

Lopes

et al. 2023

GE Port J Gastroenterol

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Colon capsule endoscopy as panendoscopy: Using current knowledge to enhance possibilities

2022

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We thank the colleagues for their interest in our study [1]. Colon capsule endoscopy (CCE) has great potential as a diagnostic tool for the entire gastrointestinal tract. However, we agree that limiting factors such as imperfect colon cleanliness and low completion rates currently hinder the implementation of CCE as pan-endoscopy. Although efforts must be made to optimize the abovementioned issues, other solutions should be considered in the meantime. For example, recently we found that lower body mass index and history of abdominal surgery resulted in slower CCE transit times and lower completion rates. In future practice, these factors can be considered to predict a longer capsule transit time and possibly require adjustment of the preparation and booster protocol. It was also shown that participants who took metoclopramide because of delayed stomach transit subsequently had significantly faster small bowel transit compared to those who did not take metoclopramide. This suggests that likelihood of completion might be optimized by using metoclopramide in all CCE procedures, instead of waiting for a delay in stomach transit. Similar studies could be performed to determine which factors can be considered to optimize colon cleanliness. Furthermore, improvement in technical aspects of CCE, such as battery life, and practical aspects, such as the need for adequate artificial intelligence for reviewing CCE images, are warranted for further implementation of CCE as pan-endoscopy.

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Light flickering through a narrow window opening in capsule panendoscopy

Cited by 2 publications

References 8 publications

Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives

Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives

Colon capsule endoscopy as panendoscopy: Using current knowledge to enhance possibilities

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