Lightfix: A Prospective, Multi-Center Study of the Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pathological Fractures from Metastatic Bone Disease in the Humerus

Golub, Ivan J; Decilveo, Alexander P.; Topfer, Jacob; O'Connor, Ian T.; Peterson, Joel R.; Wittig, James C.

doi:10.1016/j.jamcollsurg.2016.08.073

Cited by 2 publications

(3 citation statements)

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“…Its applicability and efficacy in the current literature is well elaborated (e.g. Illuminoss®) [6,7].…”

Section: Discussionmentioning

confidence: 99%

“…In contrast to PMMA, PBS shows decreased “thermal excursion and curing time”, which favors the use in older patients presenting with further comorbidities. Vegt et al postulate the ease of implementation (minimally-invasive) and the stable reconstruction [6,7]. They reported excellent results of PBS in osteoporotic long bone fractures of the humerus, femur, fibula and distal radius/ulna [6].…”

Section: Discussionmentioning

confidence: 99%

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Augmentation of simultaneous acetabular and femoral neck fracture in osteogenesis imperfecta using photodynamic bone stabilization — A case report

Pesch

Gromer

Beirer

et al. 2019

Trauma Case Reports

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BackgroundSurgical fracture treatment in patients suffering from “osteogenesis imperfecta” (OI) is challenging and often results in unsatisfactory fixation of implants due to altered bone quality. Even the use of locking plates bears a residual risk to develop a loss of reduction leading to secondary fracture dislocation. However, the augmentation with an intramedullary photodynamic bone stabilization system (PBS) (e.g. Illuminoss®) may increase bone stability and allow for a sufficient anchorage of established implants even in OI patients.Case presentationWe report the case of a 41-year-old male patient with the diagnosis of OI. He sustained a medial femoral neck fracture (Garden type IV, Pauwels type III) and a fracture of the acetabulum (AO-Type 62-B.3) – both right-sided – after a blunt trauma during a bicycle accident. The medial femoral neck fracture was subsequently surgically treated to preserve the femoral head. After augmentation of the proximal femur with the PBS, a Dynamic Hip Screw (DHS) was implanted. After a short recovery, the acetabular fracture was surgically treated by intramedullary augmentation and locking plate fixation.The patient was discharged seven days after the surgical intervention of the acetabular fracture. Partial weight-bearing activities of the right lower extremity were performed on crutches for 6 weeks. The patient was able to do his outpatient rehabilitation program without any complications. He returned to work eight weeks after surgery. After a follow-up of four months, the patient presented full weight-bearing without assistance. No physical complaints were reported 14 months after surgery (Harris Hip Score 90).ConclusionTo the best of our knowledge, we report the augmentation with a photodynamic bone stabilization system of internal fixation techniques in an OI patient with fractures of the femoral neck and the acetabulum for the first time. This advanced surgical procedure shows the high potential of intramedullary photodynamic bone stabilization in patients with minor bone quality.

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“…Its applicability and efficacy in the current literature is well elaborated (e.g. Illuminoss®) [6,7].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Augmentation of simultaneous acetabular and femoral neck fracture in osteogenesis imperfecta using photodynamic bone stabilization — A case report

Pesch

Gromer

Beirer

et al. 2019

Trauma Case Reports

View full text Add to dashboard Cite

show abstract

“…urgical management of humeral metastatic disease can be accomplished by plate osteosynthesis (with or without intralesional curettage and cement augmentation), intramedullary nail fixation, or-the most recent option-stabilization with a photodynamic implant [1][2][3] . The IlluminOss Photodynamic Bone Stabilization System (IlluminOss Medical, Inc) involves the insertion of a Dacron balloon catheter into the medullary canal, which is then infused with a liquid, photosensitive monomer under pressure.…”

mentioning

confidence: 99%

Severe Hemodynamic Collapse During Humerus Stabilization with Photodynamic Implant

Sabharwal,

Boland,

Vaynrub

2024

JBJS Case Connector

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Case: We present 2 cases of severe hemodynamic collapse during prophylactic stabilization of impending pathologic humerus fractures using a photodynamic bone stabilization device. Both events occurred when the monomer was infused under pressure into a balloon catheter. Conclusion: We suspect that an increase in intramedullary pressure during balloon expansion may cause adverse systemic effects similar to fat embolism or bone cement implantation syndrome. Appropriate communication with the anesthesia team, invasive hemodynamic monitoring, and prophylactic vent hole creation may help mitigate or manage these adverse systemic effects.

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Lightfix: A Prospective, Multi-Center Study of the Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pathological Fractures from Metastatic Bone Disease in the Humerus

Cited by 2 publications

References 0 publications

Augmentation of simultaneous acetabular and femoral neck fracture in osteogenesis imperfecta using photodynamic bone stabilization — A case report

Augmentation of simultaneous acetabular and femoral neck fracture in osteogenesis imperfecta using photodynamic bone stabilization — A case report

Severe Hemodynamic Collapse During Humerus Stabilization with Photodynamic Implant

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