Lignan derivatives from the stem bark ofSyzygium cumini(L.) Skeels

Mir, Qurat Y; Ali, Mohammad; Alam, Prawez

doi:10.1080/14786410802038697

Cited by 14 publications

(5 citation statements)

References 7 publications

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“…'-pentaol or 3,3'-didemethyl-9-oxo-pinoresinol along with the known lignans di-demethyl-5-hydroxypinoresinol, dimethylpinoresinol, didemethoxypinoresinol, pinoresinol and 4'-methyl-5'-hydroxypinoresinol [44]. The anthocyanins occur as 3,5-, but not 3-diglucosides, of delphinidin, cyanidin, petunidin, peonidin, and malvidin.…”

Section: Medicinal Propertiesmentioning

confidence: 99%

Jamun (Syzygium cumini (L.)): A Review of Its Food and Medicinal Uses

Swami¹,

Thakor²,

Patil³

et al. 2012

FNS

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Eugenia jambolana Lam., commonly known as black plum or "jamun" is an important medicinal plant in various traditional systems of medicine. It is effective in the treatment of diabetes mellitus, inflammation, ulcers and diarrhea and preclinical studies have also shown it to possess chemopreventive, radioprotective and antineoplastic properties. The plant is rich in compounds containing anthocyanins, glucoside, ellagic acid, isoquercetin, kaemferol and myrecetin. The seeds are claimed to contain alkaloid, jambosine, and glycoside jambolin or antimellin, which halts the diastatic conversion of starch into sugar. The present review has been primed to describe the existing data on the information on traditional and medicinal use.

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Section: Medicinal Propertiesmentioning

confidence: 99%

Jamun (Syzygium cumini (L.)): A Review of Its Food and Medicinal Uses

Swami¹,

Thakor²,

Patil³

et al. 2012

FNS

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“…The leaves of S. cumini are used in the folk medicine as a remedy against diabetes, dysentery, indigestion, gastrointestinal problems, and weight loss, and as an anti-inflammatory agent, antipyretic, and antiemetic [16] [17]. Phytochemical investigations of this species have shown the presence of tannins, flavonoids, polyphenols, anthraquinones, alkaloids, lignans, and terpenoids [18] [19].…”

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confidence: 99%

Molluscicidal and Leishmanicidal Activity of the Leaf Essential Oil of Syzygium cumini (L.) Skeels from Brazil

Dias

Rodrigues

Carvalho

et al. 2013

Chemistry & Biodiversity

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The chemical composition and biological potential of the essential oil extracted from Syzygium cumini leaves collected in Brazil were examined. GC/MS Analyses revealed a high abundance of monoterpenes (87.12%) in the oil. Eleven compounds were identified, with the major components being α-pinene (31.85%), (Z)-β-ocimene (28.98%), and (E)-β-ocimene (11.71%). To evaluate the molluscicidal effect of the oil, it was tested against Biomphalaria glabrata and the LC₅₀ obtained was 90 mg/l. The essential oil also showed significant activity against Leishmania amazonensis, with an IC50 value equal to 60 mg/l. In addition, to evaluate its toxicity towards a non-target organism, the essential oil was tested against Artemia salina and showed a LC₅₀ of 175 mg/l. Thus, the essential oil of S. cumini showed promising activity as a molluscicidal and leishmanicidal agent and might be valuable in combating neglected tropical diseases such as schistosomiasis and leishmaniasis. Further research is being conducted with regard to the purification and isolation of the most active essential-oil compounds.

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“…The structures of eleven known compounds 3-13 were identified as ergosterol peroxide (Lee et al, 2006) (Koo et al, 2013), (E)-coniferaldehyde (Sy and Brown, 1999), 7-O-ethylguaiacylglycerol (Comte et al, 1997), b-hydroxypropiovanillone (Lin et al, 1994), (+)-catechin (Davis et al, 1996), asarylaldehyde (Patra and Mitra, 1981), indolal (Fenn et al, 1978), 8-oxo-pinoresinol , pinoresinol (Mir et al, 2009), (+)-syringaresinol (Zhu et al, 2012) by comparison with literature values. The cytotoxicity tests for the isolates were performed using a previously reported procedure (Mosmann 1983;Yuan et al, 2013).…”

Section: Structure Elucidation and Configuration Confirmationmentioning

confidence: 99%