Linear and nonlinear optical properties of transfer ribonucleic acid (tRNA) thin solid films

Abstract

Optical measurements of one of the vital biological molecules (RNA) in the human body.

Highly nonlinear optic nucleic acid thin-solid film to generate short pulse laser

“…RNA also has higher UV radiation resilience 21 – 23 and chemical stability 24 , 25 making it a more promising candidate for practical thin solid film applications. In our prior report 26 , we experimentally confirmed that additional heat should be supplied to make RNA aqueous solutions which strongly implies that RNA can sustain a higher temperature than DNA. An appropriate viscosity of the liquid precursor is essential in TSF processes to provide uniformity in the film thickness.…”

“…An appropriate viscosity of the liquid precursor is essential in TSF processes to provide uniformity in the film thickness. RNA aqueous solution showed a viscosity 5 , 26 much less than DNA solution for the same concentrations. Therefore, conventional spin-coating processes are expected to obtain RNA TSFs more repeatably than DNA TSFs.…”

“…Despite these high potentials of RNA TSFs, most studies on RNA have been strictly confined to aqueous solutions 27 , 28 , which has restricted their solid-state device explorations in contrast to vast demonstrations by DNA-TSFs 5 , 27 – 40 . The authors' group has made an initial report on making RNA TSF 26 on silica and silicon substrates with a high uniformity using a spin-coating process. The article reported large third-order optical coefficients in RNA-TSF through femtosecond laser z-scan experiments, confirming the high potential in nonlinear optic applications.…”

Biomolecule-Based Optical Metamaterials: Design and Applications

“…RNA molecules with proper sequence motifs can self-assemble into a 3D hydrogel polymer network without the addition of any cross-linkers or any external or artificial support [ 291 ]. Films made with tRNA showed linear and nonlinear optical properties, representing a high potential in all-RNA photonic device applications and further applications to temperature sensing and thermo-optic devices [ 292 ].…”

“…There are still very few applications towards the field of optics where RNA derived from biomass has been used. The tRNA powder processed from wheat germs has been used for the assembly of RNA membranes [ 292 ]. Nanoparticles were also obtained from E. coli tRNA with divalent metal cations, which made it possible to obtain particles ranging in size from several to hundreds nanometers [ 393 ].…”