Linear lichenoid drug eruption induced by valsartan

The remarkable paradigm of segmental (mosaic) drug eruptions

“…'s case adds up to already reported, yet exceptional instances of drug eruptions occurring in a mosaic form, which include, beside FDE,[13–5] lichenoid dermatitis,[6–10] spongiotic dermatitis[11–14] and pigmented purpuric dermatosis [Table 1]. [1516] Segmental lesions were distributed along with Blashko lines in all cases.…”

Linear lichen planus along the lines of Blaschko in three adult women

“…Lichenoid drug eruptions following Blaschko's lines have rarely been described. Nonetheless, two cases of valsartan-induced linear lichenoid drug eruptions have been reported: one had a history of previous LP (Gencoglan et al, 2009). It is interesting that telmisartan induced LLP as it is structurally unique and, in addition to its angiotensin receptor-blocking properties, induces a state of endothelial cells quiescence by regulating networks of genes influencing cell growth and apoptosis (Siragusa and Sessa, 2013).…”

Letrozole Induced Linear Lichenoid Eruption in a Patient with Breast Cancer: Case Report

“…8,9 Linear lichen planus following Blaschko lines that is associated with drug usage has been reported first time by Muñoz et al and in literature there are case reports induced by bizmuth, valsartan, ibuprofen, salazopyrine and nicergoline. [1][2][3][4][5] Acquired dermatoses following Blaschko lines are termed as blaschkitis and this pattern has been explained by cellular mosaicism that is result to clone of cells with different histocompatibility antigen in a particular area of the skin. 3 Our case is also an example of linear lichenoid drug eruption that is occurred due to letrozole.…”

“…[1][2][3][4][5] We describe a case of lichenoid eruption with linear configuration induced by letrozole, third generation, aromatase inhibitor for oestrogen receptor-positive breast cancer, in a 52-year old woman who has been diagnosed breast cancer. Linear lichenoid drug eruptions following Blaschko lines are rare subtype of lichenoid drug eruptions and it is important to differentiate from zosteriform lichen planus lesions that occur due to Koebner phenomenon.…”