Linear Morphea Mimicking Lichen Striatus in Its Early Presentation

Muñoz-Garza, Fania Zamantta; Mercadè, Elena Manubens; Crespo, Esther Roè; Sanz, Lluís Puig; Torres, Eulàlia Baselga

doi:10.1111/pde.12722

Cited by 8 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Early morphea can have a subtle presentation, clinically and histologically, making it particularly difficult to diagnose early when aggressive treatment, including methotrexate and systemic corticosteroids, is likely to be most beneficial. Early linear morphea may mimic a port wine stain, pigmented purpuric dermatosis (as in our patient), Lyme disease, or lichen striatus, among other dermatoses, commonly leading to misdiagnosis and delay in treatment . One study by Johnson and colleagues noted that only approximately 40% of individuals with linear morphea were diagnosed within the first 6 months of disease onset …”

Section: Discussionmentioning

confidence: 72%

Red‐brown macules in a linear distribution on the arm

Donaldson

Hunt

Theos

2018

Pediatric Dermatology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 72%

Red‐brown macules in a linear distribution on the arm

Donaldson

Hunt

Theos

2018

Pediatric Dermatology

View full text Add to dashboard Cite

“…3 Lichen striatus, in particular, can be misleading in the initial stages as it mimics linear morphea based on clinical presentation alone. 4 Histopathological examination plays a vital role in confirming the diagnosis of linear morphea. Linear morphea characteristic histological features include epidermal atrophy, increased pigmentation of the basal layer, thickening of dermal collagen bundles, and loss of appendages.…”

Section: Discussionmentioning

confidence: 99%

“…Lichen striatus, in particular, can be misleading in the initial stages as it mimics linear morphea based on clinical presentation alone 4 . Histopathological examination plays a vital role in confirming the diagnosis of linear morphea.…”

Section: Discussionmentioning

confidence: 99%

Successful treatment with baricitinib of linear morphea following the lines of Blaschko mimicking lichen striatus

Zou,

Wei,

Yao

et al. 2023

The Journal of Dermatology

View full text Add to dashboard Cite

Linear morphea, also known as linear scleroderma, is a localized form of scleroderma characterized by the presence of lesions that follow a linear distribution pattern. Apart from the typical inflammation and fibrosis of the skin, the linear subtype of morphea often affects underlying structures such as muscles and bones, which can lead to functional limitations. Lichen striatus, a linear inflammatory skin condition, primarily affects children aged 5 to 15 years. Interestingly, both diseases can exhibit lesions that follow the lines of Blaschko. Here we report a case with linear morphea following the lines of Blaschko mimicking lichen striatus in a 4‐year‐old child. This unique case represents the first documented instance of linear morphea exhibiting a precise Blaschko pattern and being successfully treated with baricitinib. The patient received oral baricitinib at a daily dosage of 2 mg for a duration of 1 year, resulting in remarkable improvement. The majority of the lesions softened, and there was no significant disease progression or occurrence of adverse events throughout the treatment period. Recognizing linear morphea at an early stage is of utmost importance in ensuring effective treatment and preventing disfiguring sequelae. Patients suspected of lichen striatus should also be closely followed and linear morphea should be excluded during the follow‐up. The recent breakthrough in the application and the safety of baricitinib in scleroderma is also reviewed.

show abstract

“…reported a case of segmental LA refractory to conventional therapies, which responded to combination therapy with pentoxifylline and prostacyclin. Similarly, regarding another linear dermatosis affecting mostly children, Muñoz Garza et al . reported two children who presented with lichen striatus lesions preceding linear morphoea at the same site, and hypothesized that the lesion may have been linear morphoea mimicking lichen striatus from the onset.…”

mentioning

confidence: 96%