Linezolid vancomycin resistant<i>Enterococcus</i>isolated from clinical samples in Tehran hospitals

Yasliani, S; Mobarez, Ashraf Mohabati; Doust, Reza Hosseini; Satari, Mohammad; Teymornejad, O

doi:10.4103/0019-5359.55117

Cited by 20 publications

(8 citation statements)

References 15 publications

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“…During the initial database search, a total of 150 articles were found. After exclusion of the articles according to our criteria, a total of 44 articles were included in the analysis [3] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] . Among these 44 articles, 24 were associated with general patients (3071 isolates), 12 studies assessed their enterococcal populations on the basis of species (3906 isolates) and eight investigated colonization of enterococci among complicated patients with specific underlying conditions (589 isolates).…”

Section: Resultsmentioning

confidence: 99%

“…The apparent upsurge and downsurge in vancomycin resistance seems to have occurred every 2 to 3 years during the last 15 years in Iran. During 2007, 8.5% vancomycin-resistant enterococci (VRE) was reported among clinical enterococci recovered from two hospitals in Tehran [44] . In 2016, 4% VRE were isolated from patients in southeast Iran (Zabol province), which included the first reported case of vancomycin-resistant Enterococcus mundtii in Iran [18] .…”

Section: Discussionmentioning

confidence: 99%

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Rise of antibiotic resistance in clinical enterococcal isolates during 2001–2016 in Iran: a review

Asadollahi

Razavi

Asadollahi

et al. 2018

New Microbes and New Infections

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IntroductionThe clinical significance of enterococci is mostly related to its antibiotic resistance which contributes to colonization and infection, in particular amongst the hospitalized patients. The present review has examined the literature to provide a comprehensive data on enterococci antibiotic resistance during the last 20 years in Iran.MethodsSearch engines such as Google Scholar and PubMed were used to identify all Persian and English-language articles investigating enterococci in Iran from 1996 to 2017. The search terms were “enterococci”, “enterococcal”, “enterococcus”, “Iran”, “bacterial resistance”, “antibiotic resistance” and “resistance”.ResultsDecrease in the resistance trend against ampicillin, gentamycin and ciprofloxacin was observed over a period of 15 years (2001 to 2016) in Iran. During a 10 years period from 2001 to 2015, the rate of resistance among Enterococcus faecalis species was less than Enterococcus faecium. The resistancerate, however, was considerably increased for both species during this period. The mean resistance rates for vancomycin, gentamicin, ciprofloxacin, erythromycin, nitrofurantoin, chloramphenicol, trimethoprim-sulfametoxazol, imipenem and teicoplanin were higher among complicated cases (patients with underlying debilitating disorders) compared to general cases (hospitalized or outpatients with no specific underlying disorder).ConclusionsE. faecalis and E. faecium showed a rise in the mean resistance against all the antibiotics during a 10-year period from 2010 to 2015. With the exception of penicillin and ampicillin, resistance to all antibiotics was higher amongst complicated cases compared to general patients.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Rise of antibiotic resistance in clinical enterococcal isolates during 2001–2016 in Iran: a review

Asadollahi

Razavi

Asadollahi

et al. 2018

New Microbes and New Infections

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“…A study from India has shown 100 per cent susceptibility of VRE to linezolid 14 . Yasliani et al 15 reported two isolates of E. faecium resistant to linezolid from Tehran with MIC 32 µg/ml. Susceptibility of VRE to linezolid was shown to decrease to 83 per cent six months after inclusion of linezolid on the hospital antibiotic policy 16 .…”

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confidence: 99%

Antimicrobial susceptibility pattern of vancomycin resistant enterococci to newer antimicrobial agents

Gupta¹,

Singla²,

Behl³

et al. 2015

Indian J Med Res

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“…Over time, E. gallinarum vanC has been isolated from hospital, livestock as well as humans possessing vanC-1 and vanA gene clusters as E. gallinarum/casseliflavus has been reported to harbor vanA, -B and -D (Haenni et al, 2009;Neves et al, 2009) with a high degree of resistance to linezolid and vancomycin (Yasliani et al, 2009;Praharaj et al, 2013). This is so as E. casseliflavus/gallinarum is known to possess resistant inducible genes of vanC with vanC being elicited constitutively (Panesso et al, 2005).…”

Section: November 2019 | Volume 7 | Issue 11 | Page 1023mentioning

confidence: 99%

Vancomycin-Resistant Enterococcus: Issues in Human Health, Animal Health, Resistant Mechanisms and the Malaysian Paradox

Wada¹,

Harun²,

Yean³

et al. 2019

Adv. Anim. Vet. Sci.

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E nterococcus occur naturally in the surroundings and are an important constituents of the gut microbes in humans and animals (van Schaik and Willems, 2010; Boehm and Sassoubre, 2014). Enterococcus species detected till date are over 50 (Bonacina et al., 2016; Guzman et al., 2016). In human guts, Enterococcus faecalis occur mostly followed by E. faecium while in livestock, E. faecium is the major species followed by E. faecalis, E. cecorum and sometimes E. hirae (Klein, 2003; Guzman et al., 2016). Urinary tract infections, inflammation of the endocardium, and blood infection are linked to Enterococci and these conditions are particularly worse in immunocompromised individuals (Lebreton et al., 2014; Neelakanta et al., 2015). Nosocomial and drug-resistant infections are largely caused by E. faecium and E. faecalis and these pathogens are largely accountable for human vancomycin-resistant enterococci (VRE) infections (van Schaik and Willems, 2010; Leb-reton et al., 2013). The spotlight was beamed on Enterococci as a significant hospital-acquired microbe in regard to their innate resistance to various antibiotics, the rate at which they become highly infectious and the factors responsible for their multidrug resistance (Balli et al., 2014; Bourgeois-Nicolaos et al., 2014; Kristich et al., 2014). Epidemiological reports have continued to implicate VRE in regards to its effect on health, the economy and continuous infection in humans (Byappanahalli et al., 2012; Shaghaghian et al., 2012) following to their earliest documentation in the 80s (Leclercq et al., 1988; Uttley et al., 1988). Though VRE is hardly seen in pets, they rarely cause infection in animals (Willems et al., 2011). Studies have suggested that Enterococcus resistant to vancomycin act as a reservoir and source of resistant genes. This article, therefore, discusses and reviews VRE, its phenotypic and genotypic characteristics, antimicrobial resistance, virulence factors and zoonotic potential. Finally, it sheds review Article Abstract | Enterococcus is a major constituent of the intestinal flora and environment. They are a hardy organism and can survive harsh prevailing environmental factors and hosts. Over time, the constant and heavy usage of antibiotics like vancomycin in treating infection caused by them has resulted in their development of resistance and virulent characteristics. VRE infections in animals are uncommon, and even so in pets. The reverse is, however, the case with human VRE infection. VRE are of great importance in public health, animal and medical health. The adaptability and complexity of the VRE genes have resulted in the appearance of resistant species in a wide range of environment and hosts which will invariably allow the host and environment to act as a reservoir. This article, therefore, discusses and reviews VRE, its phenotypic and genotypic characteristics, antimicrobial resistance, virulence factors and zoonotic potential. Finally, it sheds light on the situation of VRE in Malaysia. This would be the first review to look at V...

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Linezolid vancomycin resistantEnterococcusisolated from clinical samples in Tehran hospitals

Cited by 20 publications

References 15 publications

Rise of antibiotic resistance in clinical enterococcal isolates during 2001–2016 in Iran: a review

Rise of antibiotic resistance in clinical enterococcal isolates during 2001–2016 in Iran: a review

Antimicrobial susceptibility pattern of vancomycin resistant enterococci to newer antimicrobial agents

Vancomycin-Resistant Enterococcus: Issues in Human Health, Animal Health, Resistant Mechanisms and the Malaysian Paradox

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