Lipase-catalyzed synthesis of xylitol monoesters: solvent engineering approach

Lipase-Catalyzed Synthesis of 6-O-D-Glucosyldecanoate inTert-Butanol: Reaction Optimization and Effect of Mixing Power Input

“…enzyme catalyzed sugar esters production has attracted growing interest among researchers as it is inexpensive, harmless to the environment due to their complete biodegradability and is known to be non-toxic to human health (5,6,7). Several researches for process improvement on the enzyme catalyzed sugar esters production have been reported; none reported on the optimization of 6-O-D-glucosyldecanoate in non aqueous medium, which addressed the complex challenges in the synthesis process.…”

Chemoenzymatic synthesis: a strategy to obtain xylitol monoesters

“…7 For the synthesis of xylitol monoesters acylated on the primary hydroxyl group, the control of regioselectivity in acylation reactions is a critical issue. 9 To overcome such limitations, the literature suggests several strategies such as solvent engineering, use of transesterification reaction instead of direct esterification or modification of the sugar structure. 7,9 In this work, xylitol monoesters were prepared by chemoenzymatic synthesis, in which, in the first step, xylitol was made soluble in organic solvent by chemo-protecting reaction ( Fig.…”

“…This enzyme is also able to accept a large variety of substrates, including bulky and sterically hindered molecules. 9 …”

Application of lipase immobilized on nylon‐6 for the synthesis of butyl acetate by transesterification reaction inn‐heptane

“…[2][3][4][5][6] In the last few years, there has been an increasing interest in the use of enzymes for the biosynthesis of molecules in organic media. [7][8][9] At present, many esters are industrially manufactured by chemical methods. However, chemical methods involve high temperature or high pressure; it is difficult in many cases to esterify unstable substances such as polyunsaturated fatty acids, ascorbic acid, and polyols.…”