Liposome mediated encapsulation and role of chitosan on modulating liposomal stability to deliver potential bioactives-A review

Joy, Jean Mary; Amruth, P.; M, Rosemol Jacob; Dara, Pavan Kumar; Renuka, V.; Anandan, R.

doi:10.1016/j.fhfh.2023.100142

Cited by 11 publications

(5 citation statements)

References 126 publications

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“…Compared to the P-ACPL, the sustained release effect of the P-ACPLG is more obvious. This is due to the Due to the accumulation of colloidal particles caused by the long-term storage of liposomes [39], P-ACPLG was prepared by dispersing liposomes into a gel matrix. As shown in Figure 3B, after the P-ACPLG was stored at room temperature, 4 • C, and −20 • C for 60 days, the encapsulation rates of the P-ACPLG at −20 • C, 4 • C, and normal temperature were 65.63%, 75.32%, and 58.41%, and the leakage rates were 25.05%, 13.98%, and 33.29%, respectively.…”

Section: Determination Of Phosphorylated Auricularia Cornea Var LI Po...mentioning

confidence: 99%

Preparation of Phosphorylated Auricularia cornea var. Li. Polysaccharide Liposome Gel and Analysis of Its In Vitro Antioxidant Activity

Fan,

Jiang,

et al. 2024

Foods

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In this study, Auricularia cornea var. Li. polysaccharides (ACP) were used as the research object to prepare liposome gel and determine its antioxidant activity in vitro. Phosphorylated Auricularia cornea var. Li. polysaccharides (P-ACP) were prepared via the phosphorylation of ACP by the phosphate method. Additionally, phosphorylated Auricularia cornea var. Li. polysaccharide liposomes (P-ACPL) were prepared using a reverse evaporation method. Finally, phosphorylated Auricularia cornea var. Li. polysaccharide liposome gel (P-ACPLG) was prepared by dispersing the P-ACPL in the gel matrix. The results show that the phosphorylation of the P-ACP was 15.51%, the containment rate of the P-ACPL was 84.50%, the average particle size was (192.2 ± 3.3) nm, and the particle size distribution map had a homogeneous peak, resulting in the particle dispersion being uniform and the polydispersion index (PDI) being 0.134 ± 0.021. The average Zeta potential was (−33.4 ± 0.57) mV. In addition, the in vitro antioxidant activity of the P-ACPL was slightly higher than that of the ACP and P-ACP. After the P-ACPL was emulsified into P-ACPLG, the DPPH, hydroxyl radical clearance, and reducing the ability of P-ACPL remained unchanged. In general, the P-ACPLG prepared in this study has good antioxidant activity in vitro and can retain the antioxidant activity of P-ACPL in vitro well.

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Section: Determination Of Phosphorylated Auricularia Cornea Var LI Po...mentioning

confidence: 99%

Preparation of Phosphorylated Auricularia cornea var. Li. Polysaccharide Liposome Gel and Analysis of Its In Vitro Antioxidant Activity

Fan,

Jiang,

et al. 2024

Foods

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“…It is important to note that while liposomes’ amphiphilic nature has been widely used to encapsulate various active pharmaceutical ingredients, its use for nutraceutical encapsulation is not yet well understood. 12 Therefore, this study focused on the liposomal form of a combination of hydrophobic and hydrophilic nutraceuticals. Their concentrations used enable the development of fortified or functional foods according to the World Health Organization (WHO) daily intake recommendations.…”

Section: Introductionmentioning

confidence: 99%

“…Based on current knowledge, the use of biopolymer complexes rather than individual biopolymers appears to be more promising for regulating stability and creating ‘smart’, stimulus-responsive liposomal forms of nutraceuticals. 12,20,21…”

Section: Introductionmentioning

confidence: 99%

“…27 However, the role of chitosan in the digestion and absorption of liposomes remains controversial. 12,20…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, there is still incomplete comprehension regarding the behaviour and absorption mechanisms of biopolymer-coated liposomal forms of nutraceuticals within the digestive tract. 12,20…”

Section: Introductionmentioning

confidence: 99%

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Key structural factors and intermolecular interactions underlying the formation, functional properties and behaviour in the gastrointestinal tract in vitro of the liposomal form of nutraceuticals coated with whey proteins and chitosan

Semenova,

Antipova,

Martirosova

et al. 2024

Food Funct.

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Development of Polyelectrolyte-Coated Liposomes as Nanostructured Systems for Nisin Delivery: Antimicrobial Activity and Long-Term Stability

Wienke,

Pinilla,

Contri

et al. 2024

Food Biophysics

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Liposome mediated encapsulation and role of chitosan on modulating liposomal stability to deliver potential bioactives-A review

Cited by 11 publications

References 126 publications

Preparation of Phosphorylated Auricularia cornea var. Li. Polysaccharide Liposome Gel and Analysis of Its In Vitro Antioxidant Activity

Preparation of Phosphorylated Auricularia cornea var. Li. Polysaccharide Liposome Gel and Analysis of Its In Vitro Antioxidant Activity

Key structural factors and intermolecular interactions underlying the formation, functional properties and behaviour in the gastrointestinal tract in vitro of the liposomal form of nutraceuticals coated with whey proteins and chitosan

Development of Polyelectrolyte-Coated Liposomes as Nanostructured Systems for Nisin Delivery: Antimicrobial Activity and Long-Term Stability

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