Liquid crystal nanoparticles for commercial drug delivery

Abstract

This is a repository copy of Liquid crystal nanoparticles for commercial drug delivery.

Self-Assembly of Organic Nanomaterials and Biomaterials: The Bottom-Up Approach for Functional Nanostructures Formation and Advanced Applications

“…The lipid phytantriol was shown to generate cubic LCs, that are not susceptible to esterase catalyzed hydrolysis, thus providing an additional colloidal stability to the formed phases. Moreover, phytantriol is largely employed as an active compound in the cosmetics applications for the improvement of the moisture retention [33,43].…”

“…In Figure 5C, we report the hexagonal nanostructure (polarized optical micrographs) obtained by the self-assembly of an equimolar surfactant-based mixture of bis(2-ethylhexyl) phosphoric acid/n-octylamine systems, and the corresponding 2D hexagonal molecular rearrangement at the basis of the LCs structure (top). employed as an active compound in the cosmetics applications for the improvement of the moisture retention [33,43]. Due to their ability to include a vast array of lipophilic and hydrophilic molecules, LCs nanostructures are particularly interesting for drug delivery and for tissue engineering applications [43,44].…”

“…employed as an active compound in the cosmetics applications for the improvement of the moisture retention [33,43]. Due to their ability to include a vast array of lipophilic and hydrophilic molecules, LCs nanostructures are particularly interesting for drug delivery and for tissue engineering applications [43,44]. More specifically, thermodynamically stable liquid crystalline nanocarriers (LCNs) are formed upon the water dispersion of amphiphiles molecules with lyotropic lipids (such as unsaturated monoglycerides, phospholipids, glycolipids).…”

Silica cubosomes templated by a star polymer

“…The cubosomes show high water-dispersibility, chemical stability, and oral bioavailability. [14][15][16][17] The interior of the cubosomes consists of regular interpenetrating networks with a large surface area. Therefore, polymer cubosomes are widely used in the elds of drug delivery, catalysis and so on.…”

“…Therefore, polymer cubosomes are widely used in the elds of drug delivery, catalysis and so on. 8,[16][17][18][19] For the formation of polymer cubosomes, both top-down and bottom-up methods have been applied. The examples include self-organized precipitation by slow evaporation of a good solvent from a polymer solution containing both poor and good solvents, [20][21][22][23] a spray drying technique for the synthesis of cubosomes from dry powder, 24,25 ash nanoprecipitation, spontaneous emulsication, etc.…”