Lithium distribution in experimental inflammation of brain and spinal cord

Staying at the crossroads: assessment of the potential of serum lithium monitoring in predicting an ideal lithium dose

“…21 The active transport of lithium allows its concentration at specific systems and organs of the body, such as central nervous system (CNS) and muscles. 22 Actually, lithium levels vary even in the CNS, where there is a higher concentration in the brain than in the spinal cord, 23 and the lithium distribution through brain structures may also vary according to the administered doses. 24 In this way, measurements of lithium in a system may not necessarily predict its levels in another one.…”