1997
DOI: 10.1007/bf02916252
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Lithium vs carbamazepine in the maintenance treatment of schizoaffective disorder: a randomised study

Abstract: In a randomised multicentre study, the prophylactic efficacy of lithium and carbamazepine was compared in schizoaffective disorder. A total of 90 ICD-9 schizoaffective patients were included in the maintenance phase (2.5 years). They were also diagnosed according to RDC and DSM-III-R and classified into subgroups. Mean serum levels were 0.58 +/- 0.12 mmol/l for lithium and 6.4 +/- 1.5 micrograms/ml for carbamazepine (mean dose 643 +/- 179 mg/d). Outcome criteria were hospitalisation, recurrence, concomitant ps… Show more

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Cited by 77 publications
(61 citation statements)
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“…This might have led them to discontinue treatment with carbamazepine earlier than a treatment with lithium. However, reasons for dropout appear quite appropriate and do not seem to be related to an excessive cautiousness of the participating psychiatrists [41,42]. Nevertheless, the present results might be biased by the clinical experience of the physicians.…”
Section: Discussionmentioning
confidence: 62%
See 1 more Smart Citation
“…This might have led them to discontinue treatment with carbamazepine earlier than a treatment with lithium. However, reasons for dropout appear quite appropriate and do not seem to be related to an excessive cautiousness of the participating psychiatrists [41,42]. Nevertheless, the present results might be biased by the clinical experience of the physicians.…”
Section: Discussionmentioning
confidence: 62%
“…; table 4). The most frequently observed side effect leading to carbamazepine-discontinuation was allergic skin reactions at the beginning of the treatment (for details see Greil et al [41,42]). …”
Section: Side Effects and Patients' Satisfactionmentioning
confidence: 99%
“…These studies have involved the comparison of specific products to placebo, competing medications, or other forms of treatment [25][26][27]. Also, these studies have been primarily conducted within clinical trials and are limited to a particular medication class or disease state [25][26][27].…”
Section: Discussionmentioning
confidence: 99%
“…These studies have involved the comparison of specific products to placebo, competing medications, or other forms of treatment [25][26][27]. Also, these studies have been primarily conducted within clinical trials and are limited to a particular medication class or disease state [25][26][27]. The current study addressed gaps in the literature of treatment satisfaction related to medication use by including all medication classes and demonstrated relationships between several important theoretical constructs in a real world setting.…”
Section: Discussionmentioning
confidence: 99%
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