Live birth after ovarian tissue autotransplantation following overnight transportation before cryopreservation

Dittrich, Ralf; Lotz, Laura; Keck, G.; Hoffmann, Inge; Mueller, Andreas; Beckmann, Matthias W.; Ven, H. van der; Montag, Markus

doi:10.1016/j.fertnstert.2011.11.047

Cited by 174 publications

(126 citation statements)

References 18 publications

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“…The source of cortical tissue stored might originate from healthy cortical tissue attached to the capsule, which has been removed during the surgery and of cortical fragments that are loosely attached to the ovary at the end of dissection. Ovarian cortical tissue collection can be performed at any center operating for endometriosis and there is no need for patients' referral since the tissue can be safely transported prior to freezing to fertility preservation center [54].…”

Section: Ovarian Tissue Cryopreservationmentioning

confidence: 99%

The role of fertility preservation in patients with endometriosis

Carrillo

Seidman

Cittadini

et al. 2016

J Assist Reprod Genet

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Patients affected with severe endometriosis are at significant risk for ovarian tissue damage, which may lead to infertility, reduced response to ovarian stimulation, and occasionally, premature ovarian failure. The risk for a compromised ovarian reserve in young patients is especially high following repeated surgical intervention and in the presence of bilateral endometriomas. In many cases, enhanced loss of ovarian reserve may also result from the damaging effect of the pathologic process on follicle reservoir even without surgical interventions. Women diagnosed with severe endometriosis and those designated for extensive ovarian surgical intervention are frequently not planning to conceive. In light of recent advances in fertility preservation techniques (FPT), such as oocytes and ovarian tissue freezing, as well as their increasing success rates, we critically evaluate the options for FPT in patients suffering from endometriosis. Personalized counseling should be offered to all patients with endometriosis taking into account age, extent of ovarian involvement, current ovarian reserve, previous and impending surgeries for endometriosis, along with current success rates and possible risks associated with FPT.

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Section: Ovarian Tissue Cryopreservationmentioning

confidence: 99%

The role of fertility preservation in patients with endometriosis

Carrillo

Seidman

Cittadini

et al. 2016

J Assist Reprod Genet

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“…Thus far, at least 30 live births have been reported following cryopreservation and autotransplantation of ovarian tissue. [1] Various methods for ovarian tissue cryopreservation and thawing [2][3][4][5][6][7][8][9] are being used worldwide. Although the efficacy of cryopreservation of ovarian tissue may thus differ from one center to another, information regarding these differences is scarce.…”

Section: Introductionmentioning

confidence: 99%

“…Orthotopic autotransplantation of ovarian tissue in 30 patients who had their tissue cryopreserved in Bonn has resulted in three live births and one additional pregnancy that has ended in a spontaneous abortion, providing proof of concept for the methods used at this facility. [2] In the current study we provide a frame of reference regarding the impact of cryopreservation-thawing on ovarian tissue viability and aim to facilitate future efforts to optimize cryopreservation and thawing methods that are currently being used worldwide.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of ovarian tissue cryopreservation in a major European center

Bastings

Liebenthron

Westphal

et al. 2014

J Assist Reprod Genet

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“…Few experimental studies have tested the human ovarian tissue from both HL or NHL and failed to show evidence of ovarian involvement by lymphoma cells [18,20,24,25]. To date, 15 auto-transplantations have been reported in HL patients and 6 in NHL without any disease recurrence, knowing that the follow-up after autotransplantation in one of the HL patients is now up to 8 years [19,[26][27][28][29][30][31][32][33][34]. Nevertheless, a recent case-report showed an ovarian involvement in the histologic examination of ovarian cortex pieces in a stage III HL [15].…”

Section: Discussionmentioning

confidence: 99%