Lloyd F. Mayer, MD: a remembrance

Abstract

University, and returned to Mount Sinai for his fellowship in gastroenterology. Following that, he spent three years pursuing immunology research as a postdoctoral fellow in Henry Kunkel's laboratory at Rockefeller University. While in the Kunkel lab and afterward, Lloyd utilized a technique to generate human T-cell hybridomas to identify factors and cytokines that stimulated B cells. 1 This led to the discovery that some individuals with common variable immunodeficiency have defects in T-cell cytokines rather than defects in B cells. 2 Common to all his work-whether in immunodeficiency, mucosal immunology, or inflammatory bowel disease (IBD)-was a primary focus on humans. His talents were quickly recognized at Mount Sinai, and one year after joining the faculty he was named chief of the Division of Clinical Immunology.