Lobe-Specific Changes in Zinc Levels in the Prostate of Rats Exposed to Tributyltin Chloride

Homma-Takeda, Shino; Nishimura, Y.; Watanabe, Yoshito; Yukawa, Masae; Ueno, Shunji

doi:10.1142/s012908350500043x

Cited by 10 publications

(6 citation statements)

References 17 publications

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“…Microbeam-based elemental analyses, such as particle-induced X-ray emission (PIXE) and synchrotron radiation X-ray fluorescence (SR-XRF), are valuable for obtaining elemental profiles of small areas and the precise distributions of elements in tissues [6][7][8]. High-energy incident X-rays in SR-XRF are suitable for detecting small amounts of uranium in tissues because they excite uranium L-lines that do not interfere with major elements such as calcium and potassium, unlike uranium M-lines.…”

Section: Introductionmentioning

confidence: 99%

Elemental imaging of kidneys of adult rats exposed to uranium acetate

Homma-Takeda¹,

Terada

Nakata³

et al. 2009

Nuclear Instruments and Methods in Physics Research Section B:

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Section: Introductionmentioning

confidence: 99%

Elemental imaging of kidneys of adult rats exposed to uranium acetate

Homma-Takeda¹,

Terada

Nakata³

et al. 2009

Nuclear Instruments and Methods in Physics Research Section B:

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“…Ion PIXE provides multi-elemental capability, which allows the simultaneous comparison of distribution of several elements inside the same specimen [401][402][403][404][405][406][407][408][409][410].…”

Section: Ion Beam Analysis Techniquesmentioning

confidence: 99%

Functionalized nanomaterials: their use as contrast agents in bioimaging: mono- and multimodal approaches

Trequesser¹,

Seznec²,

Delville³

2016

Nano Online

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The successful development of nanomaterials illustrates the considerable interest in the development of new molecular probes for medical diagnosis and imaging. Substantial progress was made in synthesis protocol and characterization of these materials whereas toxicological issues are sometimes incomplete. Nanoparticle-based contrast agents tend to become efficient tools for enhancing medical diagnostics and surgery for a wide range of 2 imaging modalities. Multimodal nanoparticles (NPs) are much more efficient than conventional molecular-scale contrast agents. They provide new abilities for in vivo detection and enhanced targeting efficiencies through longer circulation times, designed clearance pathways, and multiple binding capacities. Properly protected, they can safely be used for the fabrication of various functional systems with targeting properties, reduced toxicity and proper removal from the body. This review mainly describes the advances in the development of mono-to multimodal NPs and their in vitro and in vivo relevant biomedical applications ranging from imaging and tracking to cancer treatment. Besides specific applications for classical imaging, (MRI, PET, CT, US, PAI) are also mentioned less common imaging techniques such as terahertz molecular imaging (THMI) or ion beam analysis (IBA).Perspectives on multimodal theranostic NPs and their potential for clinical advances are also mentioned.

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“…Elemental proles of the ne structure of tissues and cells are also obtained by irradiation of a microbeam onto the aimed site (spot analysis). [270][271][272] During micro-PIXE analysis, scanning transmission ion microscopy (STIM) images are obtained simultaneously in addition to the elemental maps. Thus, it is easy to relate the elemental maps to the ne structure of tissues.…”

Section: Microbeam Elemental Analysis For Radiation Protection Studiesmentioning

confidence: 99%