We study the problems of uniqueness for Hardy–Hénon parabolic equations, which are semilinear heat equations with the singular potential (Hardy type) or the increasing potential (Hénon type) in the nonlinear term. To deal with the Hardy–Hénon type nonlinearities, we employ weighted Lorentz spaces as solution spaces. We prove unconditional uniqueness and non-uniqueness, and we establish uniqueness criterion for Hardy–Hénon parabolic equations in the weighted Lorentz spaces. The results extend the previous works on the Fujita equation and Hardy equations in Lebesgue spaces.