2024
DOI: 10.1097/ppo.0000000000000711
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Local and Systemic Management Options for Melanoma Brain Metastases

Afsaneh Amouzegar,
Hussein A. Tawbi

Abstract: Development of brain metastasis is one of the most serious complications of advanced melanoma, carrying a significant burden of morbidity and mortality. Although advances in local treatment modalities such as stereotactic radiosurgery and breakthrough systemic therapies including immunotherapy and targeted therapies have improved the outcomes of patients with metastatic melanoma, management of patients with melanoma brain metastases (MBMs) remains challenging. Notably, patients with MBMs have historically been… Show more

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