Local excision and endoscopic posterior mesorectal resection <i>versus</i> low anterior resection in T1 rectal cancer

Tarantino, Ignazio; Hetzer, Franc; Warschkow, René; Zünd, Michael; Stein, Hubert J.; Zerz, Andreas

doi:10.1002/bjs.6133

Cited by 24 publications

(15 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additional laparoscopic excision of lymph node basins may provide a means to ensure correct staging in selected patients undergoing local excision and may eventually allow for equivalent oncological outcome while minimizing morbidity further. 18 In addition, laparoscopic sentinel lymph node mapping may provide means to identify positive lymph nodes. 19 Technological advances have led to rapid advances in endoscopic management of adenomas and early colorectal cancer in recent years.…”

Section: Discussionmentioning

confidence: 99%

Survival Outcome of Local Excision versus Radical Resection of Colon or Rectal Carcinoma

et al. 2013

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Survival Outcome of Local Excision versus Radical Resection of Colon or Rectal Carcinoma

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Endoscopic posterior mesorectal excision, which allows for complete tumor staging after LE by the removal of local lymph nodes, is also another promising approach in the management of rectal cancer in the lower third of the rectum (20). Although technically demanding, preliminary evidence suggests that this minimally invasive technique, when combined with LE in a two-step procedure, has lower morbidity than low anterior resection and the potential to reduce local recurrence after LE by accurately assessing lymph node involvement (21).…”

Section: Discussionmentioning

confidence: 99%

Brachytherapy and Local Excision for Sphincter Preservation in T1 and T2 Rectal Cancer

Grimard¹,

Stern²,

Spaans³

2009

International Journal of Radiation Oncology*Biology*Physics

View full text Add to dashboard Cite

“…Recently, endoscopic posterior mesorectal resection following local excision or TEM for T1 rectal cancer was compared with LAR, showing lower morbidity rates than LAR and better locoregional control rates compared with local excision alone. However, in both groups (LAR and local excision/TEM) the node-positive patients received adjuvant chemoradiotherapy, which might have delayed the development of local recurrences, biasing the initial good results [23]. …”

Section: Discussionmentioning

confidence: 99%

Transanal Endoscopic Microsurgery for Local Excision of Rectal Lesions: Is There a Learning Curve

Koebrugge

Bosscha

Ernst³

2009

Dig Surg

View full text Add to dashboard Cite

Background: Transanal endoscopic microsurgery (TEM) is a minimally invasive technique for the local resection of benign and stage T1 rectal lesions in selected patients, associated with lower morbidity and mortality rates than open surgery. We present our initial results and assess whether experience influences outcome after TEM. Methods: This was a prospective descriptive survey. All patients undergoing TEM for tubulovillous adenoma or carcinoma between 2002 and 2007 were included. Results: A total of 105 patients were included. Median age was 68 years. Median distance of the lesion from the anal verge was 7.0 cm; median operating time was 90 min. In 10 patients, the peritoneum was opened. Six procedures were converted to (low) anterior resections. Postoperative staging revealed 77 tubulovillous adenomas, 22 stage T1, 5 stage T2 and 1 stage T3 carcinomas; tumor resection was radical in 86%. The postoperative complication rate was 7.6%. Length of hospital stay, operating time and complications significantly diminished over time. After a median follow-up of 27 months, 8 recurrences occurred (7.6%). Conclusion: TEM is a safe technique with low morbidity and recurrence rates. Over time, experience leads to a reduction in operation time, lenght of patients’ hospital stay and complication rate. TEM remains the treatment of choice for benign lesions and stage T1 rectal carcinomas in selected patients.

show abstract

Local excision and endoscopic posterior mesorectal resection versus low anterior resection in T1 rectal cancer

Abstract: EPMR after TE is a safe option for T1 rectal cancer. This two-stage procedure has a lower morbidity than LAR and may reduce locoregional recurrence compared with TE alone.

Cited by 24 publications

References 27 publications

Survival Outcome of Local Excision versus Radical Resection of Colon or Rectal Carcinoma

Survival Outcome of Local Excision versus Radical Resection of Colon or Rectal Carcinoma

Brachytherapy and Local Excision for Sphincter Preservation in T1 and T2 Rectal Cancer

Transanal Endoscopic Microsurgery for Local Excision of Rectal Lesions: Is There a Learning Curve

Contact Info

Product

Resources

About