Local Haemodynamics and Shear Stress in Cuffed and Straight PTFE-venous Anastomoses: An in-vitro Comparison using Particle Image Velocimetry

Heise, Michael; Schmidt, Sven; Krüger, U.; Pfitzmann, Robert; Scholz, Hans; Settmacher, Utz

doi:10.1016/s1078-5884(03)00243-0

Cited by 28 publications

(28 citation statements)

References 30 publications

(14 reference statements)

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“…Open surgical procedures, such as bypass operations still have an important role in today's vascular surgery [1][2][3][4][5] own veins are statistically proved to have twice as more patency rates than the artificial grafts [6][7][8] .…”

Section: Introductionmentioning

confidence: 99%

Early postoperative changes in hematological, erythrocyte aggregation and blood coagulation parameters after unilateral implantation of polytetrafluoroethylene vascular graft in the femoral artery of beagle dogs

et al. 2014

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PURPOSE:The failure of small-caliber vascular grafts still means a serious problem. Concerning the early postoperative complications we aimed to investigate the hemostaseological and hemorheological aspects of this issue in a canine model. METHODS:In the Control group only anesthesia was induced. In the Grafted group under general anesthesia a 3.5-cm segment was resected unilaterally from the femoral artery and replaced with a PTFE graft (diameter: 3 mm). On the 1 st -3 rd -5 th -7 th and 14 th postoperative days the skin temperature of both hind limbs was measured, and blood sampling occurred for hematological, hemostaseological and hemorheological tests. RESULTS:The skin temperature of the operated versus intact limbs did not differ. In the Grafted group leukocyte count was elevated by the 1 st postoperative day, while platelet count increased over the entire follow-up period. Fibrinogen concentration rose on the 1 st -5 th days, activated partial thromboplastin time increased on the 3 rd -7 th days. Erythrocyte aggregation was enhanced significantly on the 1 st -5 th days. In specimens taken on the 14 th day, histologically we found matured thrombus narrowing the graft lumen. CONCLUSIONS:Small-caliber PTFE graft implantation into the femoral artery caused significant changes in several hemostaseological and hemorheological parameters. However, better clarifying the factors leading to early thrombosis of these grafts needs further studies.Key words: Vascular Grafting. Graft Occlusion, Vascular. Erythrocyte Aggregation. Blood Coagulation. Models, Animal. Dogs. Early postoperative changes in hematological, erythrocyte aggregation and blood coagulation parameters after unilateral implantation of polytetrafluoroethylene vascular graft in the femoral artery of beagle dogs

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Section: Introductionmentioning

confidence: 99%

Early postoperative changes in hematological, erythrocyte aggregation and blood coagulation parameters after unilateral implantation of polytetrafluoroethylene vascular graft in the femoral artery of beagle dogs

et al. 2014

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“…Principle Quantity Measurement type pressure sensor [37,17,18,4,6,39,38,11,10,26] various pressure bulk, instantaneous, ≥ kHz flow sensor [35,37,17,18,6,39,38,11,10,26] various flow rate bulk, instantaneous, ≥ kHz LDV [35] optical velocity point, instantaneous, ≥ kHz VDUS [22,21] acoustic velocity point, average * , O(10) Hz PIV [4,19,12,2,27,15,28,3] optical velocity grid of points, instantaneous, O(10) Hz UIV [20] acoustic velocity grid of points, instantaneous, O(10 − 1000) Hz PLIF [3] optical concentration 2D plane, instantaneous, O(10) Hz CDUS [22,21] acoustic velocity 2D plane, average * , O(10) Hz Different methods exist to measure bulk pressure and flow rate, including Pitot tube-type and piezo-electric pressure sensors, and paddle wheel or ultrasoundbased flow rate sensors (for more information, see e.g. [36]).…”

Section: Methodsmentioning

confidence: 99%

“…The use of experimental modelling to verify a computational model is also seen in the case of AVGs [38,11,10,26]. However, in this case experimental modelling is also used as a tool on its own [15,39,38,22,21].…”

Section: Arterio-venous Graftmentioning

confidence: 99%

“…Heise et al [15] use PIV measurements in transparent Silastic models to compare the flow velocity and vorticity fields in AVGs with a straight and a cuffed anastomosis. A pulsatile inlet flow is applied, and the test fluid is a mixture of water and glycerol that matches the viscosity of blood.…”

Section: Arterio-venous Graftmentioning

confidence: 99%

“…Paper Geometry Material Heise et al [15] Straight and Cuffed PTFE Van Tricht et al [39] Straight and Tapered PTFE Van Tricht [38] Straight PTFE Kokkalis et al [22,21] Straight and Spiral ePTFE Chen et al [11,10] Electrical Circuit Silcone Tubes Lin et al [26] ---Data not available Water-glycerol (58-42%) -500 [39] Water-glycerol (60-40%) 933, 2800 500-1500 [38] Water-glycerol (60-40%) -500, 1000, 1500 [22,21] Water-glycerol (91-9%) 570, 850, 1140, 1420, 1700 240, 360, 480, 600, 720 [11,10] Water-glycerol -600-1000 [26] ----Data not available…”

Section: Arterio-venous Graftmentioning

confidence: 99%

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Review of Experimental Modelling in Vascular Access for Hemodialysis

Drost

Alam

Houston

et al. 2017

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This paper reviews applications of experimental modelling in vascular access for hemodialysis. Different techniques that are used in in-vitro experiments are bulk pressure and flow rate measurements, Laser Doppler Velocimetry (LDV) and Vector Doppler Ultrasound (VDUS) point velocity measurements, and wholefield measurements such as Particle Image Velocimetry (PIV), Ultrasound Imaging Velocimetry (UIV), Colour Doppler Ultrasound (CDUS), and Planar Laser Induced Fluorescence (PLIF). Of these methods, the ultrasound techniques can also be used in-vivo, to provide realistic boundary conditions to in-vitro experiments or numerical simulations. In the reviewed work, experimental modelling is mainly used to support computational models, but also in some cases as a tool on its own. It is concluded that, to further advance the utility of computational modelling in vascular access research, a rigorous verification and validation procedure should be adopted. Experimental modelling can play an important role in both in-vitro The final publication is available at Springer via http://dx.doi.org/10.1007/s13239-017-0311-4 2 S. Drost et al.validation, and the quantification of the accuracy, uncertainty, and reproducibility of in-vivo measurement methods.

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Molecular Mechanisms of Hemodialysis Graft Failure

Misra

2011

Essentials of Percutaneous Dialysis Interventions

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Local Haemodynamics and Shear Stress in Cuffed and Straight PTFE-venous Anastomoses: An in-vitro Comparison using Particle Image Velocimetry

Abstract: A cuffed anastomosis type may be favourable in terms of local haemodynamics so enhancing the long-term patency of PTFE-venous grafts.

Cited by 28 publications

References 30 publications

Early postoperative changes in hematological, erythrocyte aggregation and blood coagulation parameters after unilateral implantation of polytetrafluoroethylene vascular graft in the femoral artery of beagle dogs

Early postoperative changes in hematological, erythrocyte aggregation and blood coagulation parameters after unilateral implantation of polytetrafluoroethylene vascular graft in the femoral artery of beagle dogs

Review of Experimental Modelling in Vascular Access for Hemodialysis

Molecular Mechanisms of Hemodialysis Graft Failure

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