Local Immune Responses in Ocular Virus Infection and Their Implications for Future Immunotherapy

Abstract

The ability of a human ocular system to recognize viruses as foreign and eliminate them is critical for the preservation of sight. Upon viral infection, the prevention of attachment and invasion on the ocular surface decreases the likelihood of their causing disease. The tear film, secretory IgA, cytokines, cellular specific and nonspecific immune mechanisms that act at the mucosal surface constitute the first line of defense. However, sight-threatening immunopathology can take place after these reactions. Possible immune intervention in these processes is discussed.

Evaluation of the Effect of İnfection and İmmunity on the Tear Film by Scheimpflug-Placido Disc Topography- A Case Control Study

“…All participants took the NI-BUT test between 8:30 a.m. and 10:00 a.m. Thus, we minimized issues that could affect tear film stability [ 30 , 31 ]. We selected all participants from among patients who visited the ophthalmologist for routine eye examinations.…”