Local Subcutaneous Eosinophil Leucocytic Reaction to the Inoculation of Isolated Normal or Tumour Cells in Mice

Pk, Goswami

doi:10.1038/bjc.1964.80

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…In addition, there are some basic investigations supporting the anticancer activities of Eo. Goswami reported that tissue infiltrated eosinophils reacted to the inoculation of isolated tumor cells in mice 11 . Gleich et al.…”

Section: Discussionmentioning

confidence: 99%

Tumor‐associated tissue eosinophilia of penile cancer

et al. 2002

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Background : Tumor-associated tissue eosinophilia (TATE) occurs in many kinds of cancer. This study analyzed whether TATE improves the survival of penile cancer patients. Methods : In 17 patients with penile cancer, survival was compared between the TATE-positive group and the TATE-negative group. Tissue eosinophils were observed by transmission electron microscopy.Results : In all cases, 5-year survival was 72.9% in the TATE-positive group ( n = 8) and 38.9% in the TATE-negative group ( n = 9; P = 0.131). In stage III and IV, it was 60% in the TATE-positive group ( n = 5) and 0% in the TATE-negative group ( n = 5; P = 0.058). Transmission electron microscopy images revealed the vigorous infiltration of tissue eosinophils. Conclusions : It is suggested that TATE improves the survival of patients with advanced penile cancer. However, a greater number of subjects is needed to prove statistical significance.

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Section: Discussionmentioning

confidence: 99%

Tumor‐associated tissue eosinophilia of penile cancer

et al. 2002

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“…Reports in the literature about TATE are often contradictory. Some authors proposed an anticancer activity [8][9][10][11] and improvement of survival in patients with TATE [11][12][13]. In contrast, some studies suggested that the detection of eosinophils within a tumor is a negative histological prognostic marker, associated with a more aggressive behavior [14][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Preliminary Assessment of Tumor-Associated Tissue Eosinophilia (TATE) in Canine Mast Cell Tumors: Prevalence and Prognostic Relevance and Its Association with Neoangiogenesis

Galietta

Parisi

Cocumelli

et al. 2023

Animals

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Mast cell tumor (MCT) is the most common malignant skin tumor in dogs. In order to gain more information on the prognostic markers in MCT, the role of the eosinophil granulocytes infiltrates was investigated and assessed by the evaluation of tumor-associated tissue eosinophilia (TATE) in 87 canine cutaneous MCTs. In human medicine, high TATE are often described in highly angiogenic tumors: we therefore assessed the vascular endothelial growth factor (VEGF) expression in neoplastic mast cells. TATE and VEGF expression were compared between themselves, with histological grading, immunohistochemical expression of KIT and Ki-67, and with the recurrence. We found a statistically significant correlation between TATE and Patnaik grading (p = 0.041), Kiupel grading (p = 0.022), immunohistochemical KIT expression (p = 0.015), and tumor recurrence (p = 0.000). No associations were observed with Ki-67 and VEGF expression. This is the first evaluation of TATE and its prognostic value in canine MCTs in veterinary oncology. This study suggest that this investigation could be an important source of information for this tumor and for other neoplasms.

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Tumor-associated tissue eosinophilia in nasopharyngeal carcinoma. A pathologic study of 422 primary and 138 metastatic tumors

Looi¹

1987

Cancer

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A study of biopsy specimens from 422 consecutive primary nasopharyngeal carcinomas (NPCs) revealed tumor-associated tissue eosinophilia (TATE) in a large proportion (26%) of the tumors. TATE occurred more frequently in nonkeratinizing carcinomas (NKC, 38%) than in the squamous (21%) or undifferentiated (23%) types. There was no sex predilection and no association with the presence of intratumor amyloid deposits. Stromal eosinophilia was also observed in 53 (38%) of 138 metastatic NPCs in lymph nodes, where it had occasionally led to confusion with Hodgkin's disease. TATE may be a feature of diagnostic importance in NPC, although its prognostic significance remains to be ascertained.

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Local Subcutaneous Eosinophil Leucocytic Reaction to the Inoculation of Isolated Normal or Tumour Cells in Mice

Cited by 4 publications

References 13 publications

Tumor‐associated tissue eosinophilia of penile cancer

Tumor‐associated tissue eosinophilia of penile cancer

Preliminary Assessment of Tumor-Associated Tissue Eosinophilia (TATE) in Canine Mast Cell Tumors: Prevalence and Prognostic Relevance and Its Association with Neoangiogenesis

Tumor-associated tissue eosinophilia in nasopharyngeal carcinoma. A pathologic study of 422 primary and 138 metastatic tumors

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