Localised airway narrowing in sarcoidosis.

Hadfield, J W; Page, R L; Flower, C D; Stark, J. E.

doi:10.1136/thx.37.6.443

Cited by 52 publications

(26 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In three there was stenosis of a lob ar bronchus, all on the right side, those to the upp er , the middl e and the lower lob e each being affec ted in one case. A similar ste nosis of the right upper lobe bronchus occurred in Case 3 of Hadfield et al (1982). In all there were relevant symptoms and signs, either of inspiratory and expiratory airflow limitation, or episodes of lobar or segmental collapse-consolidation.…”

Section: Bronchostenosissupporting

confidence: 60%

“…A very few cases have been reported in which functionally important narrowings of large bronchi were found at an early stage, contemporary with BHL (Benedict and Castleman, 1941;Hadfield et al, 1982) . In Cases 1 and 4 of Hadfield et al, there was good evidence that multiple narrowings of segmental or sub-segmental bronchi were contemporary with recentlydeveloping BHL, accompanied by EN in Case 1; the narrowings were shown by bronchography to be more widespread than was suggested by bronchoscopy, at which the mucosa presented a cobble-stoned appearance, and on biopsy was found to be infiltrated with sarcoid granulomas.…”

Section: Bronchostenosismentioning

confidence: 99%

See 1 more Smart Citation

Sarcoidosis

Scadding

Mitchell

1985

View full text Add to dashboard Cite

Section: Bronchostenosissupporting

confidence: 60%

Section: Bronchostenosismentioning

confidence: 99%

Sarcoidosis

Scadding

Mitchell

1985

View full text Add to dashboard Cite

“…Bronchial stenosis is rare, but can occur at any stage of the disease [18]. It results from a locally intense granulomatous process with a tendency to cicatricial stenoses.…”

Section: Other Broncho-vascular Complications and Hemoptysismentioning

confidence: 99%

CT findings in severe thoracic sarcoidosis

et al. 2004

View full text Add to dashboard Cite

Severe thoracic sarcoidosis includes manifestations with significant clinical and functional impairment and a risk of mortality. Severe thoracic sarcoidosis can take on various clinical presentations and is associated with increased morbidity. The purpose of this article was to describe the CT findings in severe thoracic sarcoidosis and to explain some of their mechanisms. Subacute respiratory insufficiency is a rare and early complication due to a high profusion of pulmonary lesions. Chronic respiratory insufficiency due to pulmonary fibrosis is a frequent and late complication. Three main CT patterns are identified: bronchial distortion, honeycombing and linear opacities. CT can be helpful in diagnosing some mechanisms of central airway obstruction such as bronchial distortion due to pulmonary fibrosis or an extrinsic bronchial compression by enlarged lymph nodes. An intrinsic narrowing of the bronchial wall by endobronchial granulomatous lesions may be suggested by CT when it shows evidence of bronchial mural thickening. Pulmonary hypertension usually occurs in patients with end-stage pulmonary disease and is related to fibrotic destruction of the distal capillary bed and to the resultant chronic hypoxemia. Several other mechanisms may contribute to the development of pulmonary hypertension including extrinsic compression of major pulmonary arteries by enlarged lymph nodes and secondary pulmonary veno-occlusive disease. Aspergilloma colonization of a cavity is the main cause of hemoptysis in sarcoidosis. Other rare causes are bronchiesctasis, necrotizing bronchial aspergillosis, semi-invasive pulmonary aspergillosis, erosion of a pulmonary artery due to a necrotic sarcoidosis lesion, necrosis of parenchymal sarcoidosis lesions and specific endobronchial macroscopic lesions.

show abstract

“…3 Initial reports suggested that obstructive ventilatory defects occur only in the late stages of the disease, associated with pulmonary fibrosis. However, occlusion of a lobar bronchus and lobar atelectasis may occur without pulmonary fibrosis due to extrinsic compression by enlarged lymph nodes or, rarely, endobronchial disease 4. Moreover, isolated endobronchial lesions, which are extremely rare in pulmonary sarcoidosis,5 may also cause obstructive ventilatory defects, as in our patient.…”

Section: Discussionmentioning

confidence: 53%

Exertional dyspnoea and nonproductive cough in a 22-year-old man

Usalan

Emri²

2000

Postgraduate Medical Journal

View full text Add to dashboard Cite

A 22-year-old man presented with a 2-year history of nonproductive cough and exertional dyspnoea. He had never smoked. Because of a diagnosis of presumed bronchial asthma about 2 years ago, he was treated with multiple bronchodilators and inhaled corticosteroids for several months but no improvement in his symptoms resulted. One year prior to admission, he had been admitted to another hospital with same complaints and pulmonary tuberculosis had been suspected. Therapy with isoniazid (300 mg/d), rifampicin (600 mg/d), and ethambutol (25 mg/kg/d) for 9 months resulted in no improvement.

show abstract

Localised airway narrowing in sarcoidosis.

Cited by 52 publications

References 9 publications

Sarcoidosis

Sarcoidosis

CT findings in severe thoracic sarcoidosis

Exertional dyspnoea and nonproductive cough in a 22-year-old man

Contact Info

Product

Resources

About