Localized mediastinal lymph-node hyperplasia resembling thymoma

Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castleman's disease

“…Such abnormalities include an elevated serum IgG4 level and numerous IgG4-positive plasma cells infiltrating the affected tissue, and these disorders are classified as IgG4-related diseases. [1][2][3][4][5][6][7][8][9][10][11] Castleman's disease is a rather rare atypical lymphoproliferative disorder 12 classified according to the histopathologic findings of the affected lymph nodes as plasma cell type, hyaline-vascular type or a mixed-type variant of the two. 13,14 Patients with the plasma cell or the mixed-type variant frequently have systemic manifestations (so-called multicentric Castleman's disease), such as low-grade fever, fatigue, loss of appetite, and weight loss.…”

Hyaline-Vascular Type Castleman’s Disease, Sarcoidosis, and Crohns Disease

“…Castleman's disease (CD) is a lymphoproliferative disorder characterized by enlarged hyperplastic lymph nodes with various pathologic features [1,2]. It is classified clinically as unicentric and multicentric types.…”

Castleman’s Disease—A Rare Diagnosis in the Retroperitoneum

“…The localized form of CD arises predominantly in the mediastinum, where it was first described by Castleman [2]. Other sites include neck, abdomen, axilla, inguinal region and in virtually all lymph node areas [5][6][7][8].…”