Localized nonlinear waves in a myelinated nerve fiber with self-excitable membrane

Abstract

We systematically study the evolution of modulated nerve impulses in a myelinated nerve fiber, where both the ionic current and membrane capacitance provides the necessary nonlinear feedbacks. This is achieved by using a perturbation technique, in which the Liénard form of the modified discrete Fitzhugh-Nagumo equation is reduced to the complex Ginzburg-Landau amplitude equation. Three distinct values of the capacitive feedback parameter are considered. At the critical value of the capacitive feedback parameter, it is shown that the dynamics of the system is governed by the dissipative nonlinear Schrödinger equation. Linear stability analysis of the system depicts the instability of plane waves, which is manifested as burst of modulated nerve impulses that fulfills the Benjamin-Feir criteria. Variations of the capacitive feedback parameter generally influences the plane wave stability and hence the type of wave profile identified in the neural network. Results of numerical simulations mainly confirms the propagation, collision, and annihilation of nerve impulses in the myelinated axon.