Localized surface plasmon resonance (LSPR) biosensor based on thermally annealed silver nanostructures with on-chip blood-plasma separation for the detection of dengue non-structural protein NS1 antigen

Suthanthiraraj, Pearlson P. A.; Sen, A. K.

doi:10.1016/j.bios.2019.02.036

Cited by 84 publications

(43 citation statements)

References 55 publications

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“…In other words, LOD is the minimum number of viruses necessary to cause a detectable change in the output signal of the sensor. For the determination of LOD a formula commonly used is- [ 83 , 90 ]

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Section: Evaluation Of Plasmonic Biosensorsmentioning

confidence: 99%

“…Absorbance spectra of the biosensor immobilized with anti-NS1 antibody (red dashed line) exhibiting wavelength shift of peak absorbance after incubation with plasma separated on-chip from whole blood samples containing (c) 0.25 μ g/mL and (d) 2 μ g/mL of dengue NS1 antigen (green solid line). (e) Plot of variation of wavelength shift with concentration of NS1 spiked into whole blood showing linearity with R2 value of 0.84 ((c)-(e) reproduced with permission from [ 90 ]). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)…”

Section: Sensing Using Plasmonic Biosensorsmentioning

confidence: 99%

“…At the same time, Sen et al [ 90 ] used thermally annealed thin silver film deposited onto silicon substrate to detect NS1 antigen of dengue virus in whole blood. Refractive index sensitivity of the biosensor was 10 −3 .…”

Section: Sensing Using Plasmonic Biosensorsmentioning

confidence: 99%

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A review on plasmonic and metamaterial based biosensing platforms for virus detection

Hassan

Sium

Islam

et al. 2021

Sensing and Bio-Sensing Research

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Due to changes in our climate and constant loss of habitat for animals, new pathogens for humans are constantly erupting. SARS-CoV-2 virus, become so infectious and deadly that they put new challenge to the whole technological advancement of healthcare. Within this very decade, several other deadly virus outbreaks were witnessed by humans such as Zika virus, Ebola virus, MERS-coronavirus etc. and there might be even more infectious and deadlier diseases in the horizon. Though conventional techniques have succeeded in detecting these viruses to some extent, these techniques are time-consuming, costly, and require trained human-resources. Plasmonic metamaterial based biosensors might pave the way to low-cost rapid virus detection. So this review discusses in details, the latest development in plasmonics and metamaterial based biosensors for virus, viral particles and antigen detection and the future direction of research in this field.

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…”

Section: Evaluation Of Plasmonic Biosensorsmentioning

confidence: 99%

Section: Sensing Using Plasmonic Biosensorsmentioning

confidence: 99%

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A review on plasmonic and metamaterial based biosensing platforms for virus detection

Hassan

Sium

Islam

et al. 2021

Sensing and Bio-Sensing Research

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“…The LSPR effect of silver nanostructures has also been reported to detect dengue NS1 antigen using an immunoassay format [ 42 ]. The creation of the metal nanostructures was obtained through the deposition of a thin, silver film onto silicon substrate via thermal annealing.…”

Section: Biosensing Strategiesmentioning

confidence: 99%

Recent Progress in Plasmonic Biosensing Schemes for Virus Detection

Mauriz

2020

Sensors

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The global burden of coronavirus disease 2019 (COVID-19) to public health and global economy has stressed the need for rapid and simple diagnostic methods. From this perspective, plasmonic-based biosensing can manage the threat of infectious diseases by providing timely virus monitoring. In recent years, many plasmonics’ platforms have embraced the challenge of offering on-site strategies to complement traditional diagnostic methods relying on the polymerase chain reaction (PCR) and enzyme-linked immunosorbent assays (ELISA). This review compiled recent progress on the development of novel plasmonic sensing schemes for the effective control of virus-related diseases. A special focus was set on the utilization of plasmonic nanostructures in combination with other detection formats involving colorimetric, fluorescence, luminescence, or Raman scattering enhancement. The quantification of different viruses (e.g., hepatitis virus, influenza virus, norovirus, dengue virus, Ebola virus, Zika virus) with particular attention to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was reviewed from the perspective of the biomarker and the biological receptor immobilized on the sensor chip. Technological limitations including selectivity, stability, and monitoring in biological matrices were also reviewed for different plasmonic-sensing approaches.

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“…Fibre-optic LSPR biosensors [54,139] show a nearly 1000 fold higher sensitivity than LSPR sensors using aptamer functionalised gold nanodisk arrays (diameter= 100 nm, thickness = 20 nm, spacing = 200 to 30 nm) [55]. The sensitivity of virus detection has been reported to improve by seven orders of magnitude when AuNP (diameter = 26.5 ± 0.5 nm)-quantum dot (QD) nanoconjugates [147] are preferred over AgNPs (diameter = 20-80 nm) [148] as plasmonic nanomaterials owing to the oxidative degradation of AgNPs. Although signal enhancement of AuNPs for virus detection is lower in the case of nanohybrids using CdSeTeS QDs (size = 10.1 ± 2.9 nm) [137,149] or CdZnSeS QDs (size = 4.8 ± 0.6 nm) [147], a 33-fold lower LOD was reported when CdSeS QDs (size = 2.7-7.8 nm) were functionalised with a molecular beacon to obtain hairpin hybridisation assays [146].…”

Section: Localised Surface Plasmon Resonance Sensors For Biomedical Dmentioning

confidence: 99%

Recent Progress in Optical Sensors for Biomedical Diagnostics

Pirzada

Altıntaş

2020

Micromachines

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In recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject. Optical sensors show versatility amongst different receptor types and even permit the integration of different detection mechanisms. Such conjugated sensing platforms facilitate the exploitation of their neoteric synergistic characteristics for sensor fabrication. This paper covers nearly 250 research articles since 2016 representing the emerging interest in rapid, reproducible and ultrasensitive assays in clinical analysis. Therefore, we present an elaborate review of biomedical diagnostics with the help of optical sensors working on varied principles such as surface plasmon resonance, localised surface plasmon resonance, evanescent wave fluorescence, bioluminescence and several others. These sensors are capable of investigating toxins, proteins, pathogens, disease biomarkers and whole cells in varied sensing media ranging from water to buffer to more complex environments such as serum, blood or urine. Hence, the recent trends discussed in this review hold enormous potential for the widespread use of optical sensors in early-stage disease prediction and point-of-care testing devices.

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Localized surface plasmon resonance (LSPR) biosensor based on thermally annealed silver nanostructures with on-chip blood-plasma separation for the detection of dengue non-structural protein NS1 antigen

Cited by 84 publications

References 55 publications

A review on plasmonic and metamaterial based biosensing platforms for virus detection

A review on plasmonic and metamaterial based biosensing platforms for virus detection

Recent Progress in Plasmonic Biosensing Schemes for Virus Detection

Recent Progress in Optical Sensors for Biomedical Diagnostics

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