Location location location: muscle glycogen content and endurance exercise

Saunders, Bryan; Gobbi, Nathan

doi:10.1113/jp280808

Cited by 1 publication

(1 citation statement)

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“…Studies with animals and humans have shown that aerobic exercise over extended periods enhances brain activity and increases the size of various brain regions, such as the prefrontal, parietal, and temporal cortices (53)(54)(55). Furthermore, several clinical studies demonstrate the effects of aerobic exercise on improving cerebral blood flow, promoting neuroplasticity, and increasing whole-body VO2 peak oxygen consumption in patients with stroke (56)(57)(58)(59)(60). Additionally, engaging in high-intensity exercise has been shown to increase brain glutamate and gammaamino-butyric acid (GABA) levels (61,62).…”

Section: Mechanisms Of Aerobic Exercise and Its Impact On Cardiovascu...mentioning

confidence: 99%

Mechanisms and benefits of cardiac rehabilitation in individuals with stroke: emerging role of its impact on improving cardiovascular and neurovascular health

Cuccurullo,

Fleming,

Petrosyan

et al. 2024

Front. Cardiovasc. Med.

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Human and animal studies have demonstrated the mechanisms and benefits of aerobic exercise for both cardiovascular and neurovascular health. Aerobic exercise induces neuroplasticity and neurophysiologic reorganization of brain networks, improves cerebral blood flow, and increases whole-body VO2peak (peak oxygen consumption). The effectiveness of a structured cardiac rehabilitation (CR) program is well established and a vital part of the continuum of care for people with cardiovascular disease. Individuals post stroke exhibit decreased cardiovascular capacity which impacts their neurologic recovery and extends disability. Stroke survivors share the same risk factors as patients with cardiac disease and can therefore benefit significantly from a comprehensive CR program in addition to neurorehabilitation to address their cardiovascular health. The inclusion of individuals with stroke into a CR program, with appropriate adaptations, can significantly improve their cardiovascular health, promote functional recovery, and reduce future cardiovascular and cerebrovascular events thereby reducing the economic burden of stroke.

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