Long-term (10 years) prognostic value of a normal thallium-201 myocardial exercise scintigraphy in patients with coronary artery disease documented by angiography

Percutaneous Coronary Intervention of Functionally Nonsignificant Stenosis

“…In fact, these observations are in line with earlier noninvasive studies by MIBI single-photon emission computed Pijls et al May 29, 2007May 29, :2105 PCI of Nonsignificant Stenosis tomography (SPECT) in large numbers of patients indicating that the most important prognostic factor in patients with coronary artery disease is the presence and extent of inducible ischemia (25)(26)(27)(28)(29). The incidence of angiographically visible coronary artery disease increases with age and is at least 40% in a 60-year old population (30).…”

Risk Stratification by Adenosine Stress Cardiac Magnetic Resonance in Patients With Coronary Artery Stenoses of Intermediate Angiographic Severity

“…Patients with a PD detected on adenosine stress CMR seem to be at enhanced risk for the development of adverse cardiac events and to have a more pronounced need for TVR. These findings are in line with previous studies demonstrating that stress-induced myocardial ischemia is a valuable prognostic marker for patients with stable AP as proven by various studies using the SPECT technique (4,(22)(23)(24) or pharmacological stress echocardiography (25)(26)(27)(28). In patients with intermediate stenoses, the DEFER (Deferral Versus Performance of PTCA in Patients Without Documented Ischemia) study (6) showed that the 5-year outcome of patients after deferral of PCI was excellent and could not be improved by stenting.…”

The Prognostic Value of Normal Exercise Myocardial Perfusion Imaging and Exercise Echocardiography

“…Among these, 148 full-text articles evaluating the prognostic utility of exercise MPI or exercise echocardiography were reviewed, and 20 studies were found to be eligible for the systematic review. Of the 148 full-text articles reviewed, 17 did not address the research question (15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31), 18 were excluded because they used pharmacologic rather than exercise stress (32-49), 27 did not include primary data on event rates that could be combined in a meta-analysis (47,50 -75), 16 did not address a population with known or suspected CAD (76 -91), 5 evaluated only hospitalized patients or patients evaluated for chest pain syndromes in the emergency department (92)(93)(94)(95)(96), 16 included only patients with angiographically proven CAD or positive tests (97)(98)(99)(100)(101)(102)(103)(104)(105)(106)(107)(108)(109)(110)(111)(112), 21 were potentially overlapping patient populations of other studies (53,(113)(114)(115)…”