Long-term anatomical and functional outcomes of idiopathic macular hole surgery. The yield of spectral-domain OCT combined with microperimetry

Bonnabel, A; Bron, Alain M.; Isaico, Rodica; Dugas, B.; Nicot, Frédéric; Creuzot‐Garcher, Catherine

doi:10.1007/s00417-013-2339-y

“…However, anatomical closure of a hole does not always correlate with a good functional result (6,17,18) . Although various preoperative SD-OCT parameters have been examined to estimate postoperative visual prognosis, studies have reported the lack of any consistent volumetric or structural feature that is closely correlated with anatomical and functional surgical successes (15)(16)(17)(18) . In this study, there was no statistical difference in MHV measurements between eyes with and without disease recurrence; however, lower preoperative BCVA scores were found in eyes with relapsing MH.…”

Section: Discussionmentioning

confidence: 99%

Choroidal changes in pre-eclampsia during pregnancy and the postpartum period: comparison with healthy pregnancy

Duru¹,

Ulusoy²,

Özköse³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Registration number of clinical trials registry: 2013/43-16. ABSTRACTPurpose: To evaluate the association between macular hole volume (MHV) and postoperative central macular thickness (CMT) using spectral-domain optical coherence tomography (SD-OCT). Methods: Thirty-three eyes of 30 patients with a large full-thickness idiopathic macular hole with or without vitreomacular traction who underwent surgical intervention were included in this cross-sectional study. Complete ophthalmological examination, including SD-OCT, was performed for all participants during the pre-and postoperative visits. MHV was preoperatively measured using SD-OCT, which captured the widest cross-sectional image of the hole. For normal distribution analysis of the data, the Kolmogorov-Smirnov test was performed, and for statistical analyses, chi-square, Student's t-test, Mann-Whitney U test, and Pearson's correlation coefficient test were performed. Results: Mean preoperative best-corrected visual acuity (BCVA) and MHV were found to be 0.99 ± 0.36 (range, 0.3-2.0) logMAR and 0.139 ± 0.076 (range, 0.004-0.318) mm 3 , respectively. Mean follow-up was 16.3 ± 14.3 (range, 3-50) months. No statistical correlations were found between MHV and postoperative BCVA (p=0.588) and between MHV and disease recurrence (p=0.544). A weak negative correlation existed between MHV and final CMT scores (p=0.04, r=-0.383). Conclusions: Greater MHV was found to be weakly associated with lower postoperative CMT scores. Keywords:Retinal perforations/surgery; Tomography, optical coherence; Vitrectomy; Macula lutea; Postoperative period (variação de 0,004-0,318). O seguimento médio foi de 16,3 ± 14,3 meses (variação de 3-50). Não foram encontradas correlações estatísticas entre 588), bem como MHV e recorrência da doença (p=0,544). Uma fraca correlação negativa estava presente entre MHV e pontuações finais CMT (p=0,04,383 RESUMO Objetivo: Avaliar a relação entre o volume do buraco macular (MHV) e a espessura macular central pós-operatória (CMT) por meio da tomografia de coerência óptica de domínio espectral (SD-OCT

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“…Furthermore, a significant correlation between the presence of such abnormalities and postoperative visual prognosis has been recently reported (16)(17)(18)(19)(20) . In this study, MHV was not found to be associated with the postoperative re-establishment of any of the studied parameters of external retinal microstructure.…”

Section: Discussionmentioning

confidence: 96%

“…The data were stored in a computerized database and analyzed using Statistical Package for Scientific Studies for Windows v. 16.0 (SPSS Inc., Chicago, IL, USA). Normal distribution analysis of the data was performed using the Kolmogorov-Smirnov test; moreover, the chi-square test, the paired t-test, Student's t-test, and the MannWhitney U test were performed for statistical analyses.…”

Section: Methodsmentioning

confidence: 99%

“…Manual quantification of MH width and height can be provided using SD-OCT, which mainly identifies the presence of perifoveal cystoid edema and vitreomacular traction (VMT) and the integrity of perifoveal external retinal microstructures. The impact of preoperative OCT measurements on diagnosing or staging idiopathic MH and its predictive value for postoperative anatomical and functional outcomes have been previously investigated (14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24) . However, to the best of our knowledge, no study has elucidated the association between preoperative macular hole volume (MHV) and postoperative macular atrophy as a tool for predicting postoperative visual outcome.…”

Section: Introductionmentioning

confidence: 99%

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Effect of macular hole volume on postoperative central macular thickness

Öztürk

¹

,

Karahan

²

,

Er

³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Registration number of clinical trials registry: 2013/43-16. ABSTRACTPurpose: To evaluate the association between macular hole volume (MHV) and postoperative central macular thickness (CMT) using spectral-domain optical coherence tomography (SD-OCT). Methods: Thirty-three eyes of 30 patients with a large full-thickness idiopathic macular hole with or without vitreomacular traction who underwent surgical intervention were included in this cross-sectional study. Complete ophthalmological examination, including SD-OCT, was performed for all participants during the pre-and postoperative visits. MHV was preoperatively measured using SD-OCT, which captured the widest cross-sectional image of the hole. For normal distribution analysis of the data, the Kolmogorov-Smirnov test was performed, and for statistical analyses, chi-square, Student's t-test, Mann-Whitney U test, and Pearson's correlation coefficient test were performed. Results: Mean preoperative best-corrected visual acuity (BCVA) and MHV were found to be 0.99 ± 0.36 (range, 0.3-2.0) logMAR and 0.139 ± 0.076 (range, 0.004-0.318) mm 3 , respectively. Mean follow-up was 16.3 ± 14.3 (range, 3-50) months. No statistical correlations were found between MHV and postoperative BCVA (p=0.588) and between MHV and disease recurrence (p=0.544). A weak negative correlation existed between MHV and final CMT scores (p=0.04, r=-0.383). Conclusions: Greater MHV was found to be weakly associated with lower postoperative CMT scores. Keywords:Retinal perforations/surgery; Tomography, optical coherence; Vitrectomy; Macula lutea; Postoperative period (variação de 0,004-0,318). O seguimento médio foi de 16,3 ± 14,3 meses (variação de 3-50). Não foram encontradas correlações estatísticas entre 588), bem como MHV e recorrência da doença (p=0,544). Uma fraca correlação negativa estava presente entre MHV e pontuações finais CMT (p=0,04,383 RESUMO Objetivo: Avaliar a relação entre o volume do buraco macular (MHV) e a espessura macular central pós-operatória (CMT) por meio da tomografia de coerência óptica de domínio espectral (SD-OCT

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“…1,6,7 Several authors have investigated the relationship between functional disturbances and SD OCT findings in various retinal diseases including ERM. [8][9][10] It appears that integrity of external retinal layers and foveal thickness are closely correlated with visual parameters. [11][12][13] Since the first 6 cases of successful ERM removal were reported by Machemer in 1978, the surgical procedure has steadily improved.…”

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confidence: 99%

Preoperative Prognostic Factors and Predictive Score in Patients Operated On for Combined Cataract and Idiopathic Epiretinal Membrane

Kauffmann

¹

,

Ramel

²

,

Lefebvre

³

et al. 2015

American Journal of Ophthalmology

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Long-term anatomical and functional outcomes of idiopathic macular hole surgery. The yield of spectral-domain OCT combined with microperimetry

Abstract: Postoperative outer retinal layer integrity is associated with better final retinal sensitivity. Further studies are warranted to assess the role of SD-OCT and microperimetry in the pre- and postoperative evaluation of idiopathic macular holes.

Cited by 27 publications

References 27 publications

Choroidal changes in pre-eclampsia during pregnancy and the postpartum period: comparison with healthy pregnancy

Choroidal changes in pre-eclampsia during pregnancy and the postpartum period: comparison with healthy pregnancy

Effect of macular hole volume on postoperative central macular thickness

Preoperative Prognostic Factors and Predictive Score in Patients Operated On for Combined Cataract and Idiopathic Epiretinal Membrane

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