Long-term antibiotic exposure in soil is associated with changes in microbial community structure and prevalence of class 1 integrons

Abstract

Kornelia. (2016) Long-term antibiotic exposure in soil is associated with changes in microbial community structure and prevalence of class 1 integrons. FEMS Microbiology Ecology, 92 (10). fiw159. Permanent WRAP URL:http://wrap.warwick.ac.uk/84355 Copyright and reuse:The Warwick Research Archive Portal (WRAP) makes this work by researchers of the University of Warwick available open access under the following conditions. Copyright © and all moral rights to the version of the paper presented here belong to the individual author(s) and/or other copyright owners. To the extent reasonable and practicable the material made available in WRAP has been checked for eligibility before being made available.Copies of full items can be used for personal research or study, educational, or not-for profit purposes without prior permission or charge. Provided that the authors, title and full bibliographic details are credited, a hyperlink and/or URL is given for the original metadata page and the content is not changed in any way. Publisher's statement:This is a pre-copyedited, author-produced PDF of an article accepted for publication in FEMS Microbiology Ecology following peer review. The version of record (see above) is available online at http://dx.doi.org/10.1093/femsec/fiw159 A note on versions: The version presented here may differ from the published version or, version of record, if you wish to cite this item you are advised to consult the publisher's version. Please see the 'permanent WRAP URL' above for details on accessing the published version and note that access may require a subscription. Cyanobacteria, was shown to increase in abundance significantly; a curiosity given the established sensitivity of this Class to antibiotics. We hypothesise that the overrepresentation of Proteobacteria as OTUs that decreased significantly in relative abundance, coupled with the observations of an increase in integron prevalence, may represent a strong selective pressure on these taxa.

Novel Antibiotic Resistance Determinants from Agricultural Soil Exposed to Antibiotics Widely Used in Human Medicine and Animal Farming

“…displayed adaptability and responsiveness toward these specific drug exposures in recent studies (18,19,28). Using functional metagenomics, a number of ARGs were discovered, most of which encode (multi)drug transporters of all five superfamilies.…”

Antibiotic resistance genes in different animal manures and their derived organic fertilizer

“…According to previous studies, the content of enro oxacin and cipro oxacin in chicken manure were 61 300 μg/kg and 18 800 μg/kg, respectively [6]. High levels of residual antibiotics in manure provided selective pressure to the native microbial communities after the application of manure in soil [7][8][9], and bacteria could acquire antibiotic resistance genes (ARGs) via horizontal gene transfer or spontaneous mutation, thereby causing the proliferation of resistant bacteria [10][11].…”

Effect of composting and soil type on dissipation of veterinary antibiotics in land-applied manures

“…A major concern is that antibiotics released into soils could exert a selective pressure on the native microbial community (Cleary et al, 2016;Nordenholt et al, 2016) and enrich antibiotic resistant bacteria and resistance genes (Jechalke et al, 2014).…”