Long-term neurodevelopmental outcomes in children born with gastroschisis: the tiebreaker

Neurodevelopmental Outcomes After Neonatal Surgery for Major Noncardiac Anomalies

“…The incidence of neurodevelopmental delay in the subgroup of abdominal wall defects is remarkably low. This may be explained by the small sample sizes of these studies 28,32,33,46 (n = 8 and n = 17). Payne et al reported "a generally encouraging outcome of patients with gastroschisis."…”

“…After screening of title/abstract followed by full text, 23 papers 6,7,[25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44] reporting on 895 children met our inclusion and exclusion criteria and were selected for systematic review (Table 1). There was a wide range in follow-up duration and time of assessment from 12 months up to 60 months of age.…”

“…No differences were found in delay between patients with simple gastroschisis and matched control subjects. 32 Motor outcome in 8 patients with giant omphalocele, tested with the M-ABC at 6 years of age, was found to be normal. 46 …”

“…28,32,33,46 In 1 study (n = 46), neurodevelopment was assessed as part of a statesponsored follow-up program for all infants discharged from intensive care in the state of Nebraska, United States (the Developmental Tracking Infant Progress Statewide program). No differences were found in delay between patients with simple gastroschisis and matched control subjects.…”

Identifying strategies to decrease infectious complications of gastroschisis repair

“…Various outcomes have been reported in the literature related to this topic, and the results have been mixed [1,2,7,10,[12][13][14][15]. There are some reports of worse outcomes with early delivery, including an increased risk of infectious complications and poorer long-term neurodevelopmental outcomes [8,12]. Maramreddy found that gastroschisis patients delivered prior to 37 weeks gestation had a 14 times higher risk of morbidities than patients carried to term [2].…”