Long-term outcomes of the Ahmed glaucoma valve surgery in childhood glaucoma

Mofti, Alaa; Alharbi, Amjaad; Alsuhaibani, Marya; Aljaber, Ahmed; Altamimi, Lamees A.; Shadi, Ahmad; Aljadaan, Ibrahim; Malik, Rizwan

doi:10.1016/j.jaapos.2020.06.014

Cited by 14 publications

(26 citation statements)

References 34 publications

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“…The Ahmed implant is a flow-restrictive device, which theoretically reduces the risk of early hypotony, whereas the Baerveldt implant has a free flow design and thus requires additional measures to minimize the risk of early hypotony following surgery [23]. Their success rates in the studies published to date are difficult to compare in view of multiple study limitations [8,24]. However, a common feature of both drainage devices is declining efficacy over time and the need for pharmacotherapy to support surgical treatment [25].…”

Section: Glaucoma Drainage Devicesmentioning

confidence: 99%

Section: Primary Congenital Glaucomamentioning

confidence: 99%

“…Primary congenital glaucoma (PCG) is a rare disease that affects 4.8/100,000 live births [24]. The disease is caused by anomalous development of the filtration angle and the trabecular meshwork, which causes physical blockage of the outflow of aqueous humor in the filtration angle [24]. The appearance of classic PCG symptoms can be explained by an increased IOP level leading to corneal edema with associated Descemet's membrane tears (Haab's striae), increased corneal diameter, impaired fixation, and the onset of nystagmus secondary to compromised visual acuity.…”

Section: Primary Congenital Glaucomamentioning

confidence: 99%

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Current approaches to glaucoma surgery in children – glaucoma drainage devices and minimally invasive procedures

Garbowska,

Modrzejewska

2022

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Glaucoma is one of the leading causes of visual impairment and irreversible loss of vision in children worldwide. Taking into account prolonged treatment, the condition should be diagnosed as early as possible, so that an appropriate therapeutic strategy can be implemented. The choice of treatment should be guided by factors including the type of glaucoma, the patient's age, the condition of the anterior segment of the eye, the course of treatment to date, and the child's general health. In many glaucoma cases in pediatric patients, surgery (gonio-tomy, trabeculotomy) is the first-line treatment, but in recent years more and more importance has been attached to surgical procedures involving the implantation of filtration and drainage valves as well as novel surgical techniques, including minimally invasive glaucoma surgery (MIGS) via the ab interno approach. They may provide additional or alternative solutions to traditional surgical procedures in the treatment of childhood glaucoma.

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Section: Glaucoma Drainage Devicesmentioning

confidence: 99%

Section: Primary Congenital Glaucomamentioning

confidence: 99%

Section: Primary Congenital Glaucomamentioning

confidence: 99%

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Current approaches to glaucoma surgery in children – glaucoma drainage devices and minimally invasive procedures

Garbowska,

Modrzejewska

2022

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“…[6][7][8][9] The reported pediatric success rates of the most common GDDs (Baerveldt and Ahmed devices) are typically 80% to 90% in the first year, but decrease significantly over time. [10][11][12][13][14][15][16][17][18] However, many of these reports are limited by the small number of eyes and short time of follow-up. [10][11][12][13][14][15]17 Many of the larger studies with longer follow-up in children combine multiple types of GDDs, making it more difficult to measure the individual long-term success of each GDD.…”

mentioning

confidence: 99%

“…In children, glaucoma drainage device (GDD) implantation has become the predominant trabecular meshwork bypass surgery due to the more predictable postoperative course and decreased life-long risk of infection compared to trabeculectomy 6–9. The reported pediatric success rates of the most common GDDs (Baerveldt and Ahmed devices) are typically 80% to 90% in the first year, but decrease significantly over time 10–18. However, many of these reports are limited by the small number of eyes and short time of follow-up 10–15,17.…”

mentioning

confidence: 99%

Outcomes of Baerveldt Glaucoma Drainage Devices in Pediatric Eyes

Jacobson

Besirli

Bohnsack

2021

Journal of Glaucoma

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Précis: In children, Baerveldt implants showed 84% success at 1 year, but decreased to 32% at 8 years. Age, race, and glaucoma type were not risk factors for failure. Concurrent intraocular surgery was associated with complications. Purpose: Evaluate success and risk factors for failure and complications of Baerveldt glaucoma implants in children. Methods: Retrospective case series of children who underwent Baerveldt implant placement (2012-2019 by single surgeon) with ≥1 year follow-up. Ocular examination and surgical details were collected. Failure defined as intraocular pressure (IOP) <5 mm Hg or >21 mm Hg for 2 consecutive visits, need for IOP related surgery, or visually significant complication. Results: One hundred-six eyes of 76 patients underwent 110 Baerveldt placement at median 6.4 years. Baerveldt placement was combined with additional procedures in 49% with vitrectomy most common (30%). Success of first Baerveldt (per patient) was 64% at final follow-up (median 4.7 y). One-, 5-, and 8-year survival rates were 84%, 60%, and 32%, respectively. There was no difference (P=0.97) in survival between first Baerveldt and all Baerveldt surgeries. Failure of first Baerveldt was not associated with sex, age, ethnicity, prior IOP-lowering surgery, concurrent intraocular surgery, or glaucoma type. Complications occurred in 14% and were associated with concurrent surgery. Twenty-six percent required additional IOP-lowering surgery. At final follow-up, IOP and glaucoma medications were significantly decreased (P<0.0001). Eyes underwent an average of 3.8±2.3 ocular surgeries and 3.0±2.0 glaucoma surgeries. Conclusions: Baerveldt implants showed good success initially, but survival rates declined over time. No risk factors for failure of first implanted Baerveldt were identified. Concurrent surgery was associated with complications. Majority of eyes required multiple surgeries to achieve IOP control and preserve vision.

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Non-penetrating Glaucoma Surgery

Abdelrahman

2024

Childhood Glaucoma

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Long-term outcomes of the Ahmed glaucoma valve surgery in childhood glaucoma

Cited by 14 publications

References 34 publications

Current approaches to glaucoma surgery in children – glaucoma drainage devices and minimally invasive procedures

Current approaches to glaucoma surgery in children – glaucoma drainage devices and minimally invasive procedures

Outcomes of Baerveldt Glaucoma Drainage Devices in Pediatric Eyes

Non-penetrating Glaucoma Surgery

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