2008
DOI: 10.1007/s00066-008-1836-0
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Longitudinal Assessment of Parotid Function in Patients Receiving Tomotherapy for Head-and-Neck Cancer

Abstract: With the use of heLical tomography the parotid gland function can largely be preserved since the mean dose to the entire gland as well as glandular volume receiving >26 Gy can be reduced.

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Cited by 30 publications
(19 citation statements)
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References 35 publications
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“…At present, a mean dose of about 26 Gy to the parotid gland is the generally accepted threshold to preserve salivary flow. This dose level has been confirmed by several groups [9,25,28,33]. As different dose distributions can result in the same mean organ dose, threshold dose levels have been also recommended for partial volumes of the parotid gland [9,27].…”
Section: Introductionsupporting
confidence: 49%
“…At present, a mean dose of about 26 Gy to the parotid gland is the generally accepted threshold to preserve salivary flow. This dose level has been confirmed by several groups [9,25,28,33]. As different dose distributions can result in the same mean organ dose, threshold dose levels have been also recommended for partial volumes of the parotid gland [9,27].…”
Section: Introductionsupporting
confidence: 49%
“…13 Arc therapy reduces IMRT delivery time from 20 minutes to fewer than 5 minutes, while optimizing dose homogeneity and normal tissue sparing, [14][15][16][17][18][19][20][21][22][23][24][25] including parotid gland sparing. 26 Stereotactic fractionated RT allows for the generation of x-ray beams from a single electronic source, which can be rotated or moved around a central focus. Linear acceleratorbased stereotactic body RT may be used for multisession head and neck irradiation.…”
Section: Chemoradiation Therapymentioning
confidence: 99%
“…Using HT in HNC has led to better sparing of OARs, especially parotid glands [28]. An important question remains: does sparing of critical organs compromises target coverage and patient outcome?…”
Section: Introductionmentioning
confidence: 99%