Introduction: In youth swimming, researchers are interested in understanding how anthropometry and parameters related to swimming technique (biomechanics, energetics, and efficiency) influence the performance. However, there is not any review in the literature that consolidates the body of knowledge of this topic. The objective of this study was to review systematically the current body of work on the influence of determinant factors related to swimming technique (biomechanics, energetics, and efficiency) and anthropometry in the young performance of swimmers.Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to identify relevant studies.Results: After screening, 240 studies were analyzed and 59 related to swimming performance, and its determinant factors were retained for synthesis. Studies revealed a high-quality index by PEDro scale (mean score was 7.17 ± 1.40). Twenty-five studies were longitudinal designs and the remaining 34 cross-sectional designs. Most of the studies (N = 39, 66.1%) reported concurrently two or more determinant factors (anthropometrics, biomechanics, energetics, and efficiency).Conclusion: Youth swimming research relies on a multifactorial assessment. From the synthesis, it is possible to conclude that the performance of young swimmers is characterized by a multifactorial, holistic, and dynamic phenomenon. Better performance has always been related to better swimming technique and higher anthropometrics. This suggests that both anthropometrics (i.e., nature) and training (i.e., nurture) play key roles in the swimming performance of young swimmers.