Low concentration contrast medium for dual-source computed tomography coronary angiography by a combination of iterative reconstruction and low-tube-voltage technique: Feasibility study

Coronary CT angiography using low concentrated contrast media injected with high flow rates: Feasible in clinical practice

“…No significant differences in intravascular attenuation in AA, DA and proximal and distal segments of the coronary arteries were found in comparison to the standard CM group (300 mg/mL). The standard deviation of the attenuation values in all groups is considered somewhat broad, but within range of previous published data (25)(26)(27). This is an indication that attenuation values were quite variable, which might have been attributed to the variable body weight as well as other patient related factors (e.g.…”

Contrast Media Administration in Coronary Computed Tomography Angiography – A Systematic Review

“…In the vast majority of the included publications, a tube voltage of 120 kV was used. Some of the included papers either did not mention tube voltage or mention lower or various kV settings [48,59,63,70,73,74]. As different vendors and scanners were used, scan-related parameters such as collimation, slice reconstruction and kernel were not comparable and occasionally missing.…”

“…The CM concentration varied between 270 mg/ml and 400 mg/ml. However, only four CM injection protocols make use of CM concentrations below 320 mg/ml [7,15,19,73]. The variation in injection rate was higher than for CM concentrations, varying between 2.5 ml/s [19] and 6 ml/s [55,63,70].…”

Effect of reduced x-ray tube voltage, low iodine concentration contrast medium, and sinogram-affirmed iterative reconstruction on image quality and radiation dose at coronary CT angiography: Results of the prospective multicenter REALISE trial

“…Iterative reconstruction (IR) can counterbalance increases in image noise at low tube voltage compared with filtered back projection (FBP) and can reduce radiation dose requirements by 27% to 53% while preserving or enhancing diagnostic image quality at CCTA. 9e13 Earlier works have reported the potential of combining these quality and safety measures to lower contrast media requirements in CCTA, 14 head and neck angiography, 15 and hepatic CTA. 16 However, all positive CCTA patients underwent subsequent invasive coronary angiography (ICA) in this study.…”