Low cost SU-8 lift-off process to fabricate a gold/glass microelectrodes array for culturing applications

Cabello, Miguel; Domı́nguez, I.; Macías, Clara; Perdigones, Francisco; Aracil, Carmen; Quero, J.M.

doi:10.1007/s00542-020-05206-9

Cited by 3 publications

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(4) The microfabrication technology and materials of MEAs are being optimized to achieve a lower cost and faster preparation. In addition, the use of SU-8 to replace traditional SiO 2 and Si 3 N 4 insulation layers [64] and 3D printing technology to easily make MEAs (Figure 3D) [65] are pioneering attempts in this field.…”

Section: Development Direction Of In Vitro Measmentioning

confidence: 99%

Recent Progress and Perspectives on Neural Chip Platforms Integrating PDMS-Based Microfluidic Devices and Microelectrode Arrays

Liu

Yang

et al. 2023

Micromachines

View full text Add to dashboard Cite

Recent years have witnessed a spurt of progress in the application of the encoding and decoding of neural activities to drug screening, diseases diagnosis, and brain–computer interactions. To overcome the constraints of the complexity of the brain and the ethical considerations of in vivo research, neural chip platforms integrating microfluidic devices and microelectrode arrays have been raised, which can not only customize growth paths for neurons in vitro but also monitor and modulate the specialized neural networks grown on chips. Therefore, this article reviews the developmental history of chip platforms integrating microfluidic devices and microelectrode arrays. First, we review the design and application of advanced microelectrode arrays and microfluidic devices. After, we introduce the fabrication process of neural chip platforms. Finally, we highlight the recent progress on this type of chip platform as a research tool in the field of brain science and neuroscience, focusing on neuropharmacology, neurological diseases, and simplified brain models. This is a detailed and comprehensive review of neural chip platforms. This work aims to fulfill the following three goals: (1) summarize the latest design patterns and fabrication schemes of such platforms, providing a reference for the development of other new platforms; (2) generalize several important applications of chip platforms in the field of neurology, which will attract the attention of scientists in the field; and (3) propose the developmental direction of neural chip platforms integrating microfluidic devices and microelectrode arrays.

show abstract

Section: Development Direction Of In Vitro Measmentioning

confidence: 99%